node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGA84616.1 | AGA85294.1 | Psest_0003 | Psest_0698 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.592 |
AGA84616.1 | AGA86031.1 | Psest_0003 | Psest_1477 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | 0.984 |
AGA84616.1 | dnaA | Psest_0003 | Psest_0002 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.992 |
AGA84616.1 | polA | Psest_0003 | Psest_4219 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
AGA84616.1 | recF | Psest_0003 | Psest_0004 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.968 |
AGA85294.1 | AGA84616.1 | Psest_0698 | Psest_0003 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.592 |
AGA85294.1 | AGA86031.1 | Psest_0698 | Psest_1477 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | 0.753 |
AGA85294.1 | dnaA | Psest_0698 | Psest_0002 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.903 |
AGA85294.1 | polA | Psest_0698 | Psest_4219 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.653 |
AGA86029.1 | AGA86030.1 | Psest_1475 | Psest_1476 | PFAM: Uncharacterized protein conserved in bacteria (DUF2066). | Putative permease; PFAM: Domain of unknown function DUF20. | 0.646 |
AGA86029.1 | AGA86031.1 | Psest_1475 | Psest_1477 | PFAM: Uncharacterized protein conserved in bacteria (DUF2066). | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | 0.647 |
AGA86030.1 | AGA86029.1 | Psest_1476 | Psest_1475 | Putative permease; PFAM: Domain of unknown function DUF20. | PFAM: Uncharacterized protein conserved in bacteria (DUF2066). | 0.646 |
AGA86030.1 | AGA86031.1 | Psest_1476 | Psest_1477 | Putative permease; PFAM: Domain of unknown function DUF20. | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | 0.801 |
AGA86031.1 | AGA84616.1 | Psest_1477 | Psest_0003 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.984 |
AGA86031.1 | AGA85294.1 | Psest_1477 | Psest_0698 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.753 |
AGA86031.1 | AGA86029.1 | Psest_1477 | Psest_1475 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | PFAM: Uncharacterized protein conserved in bacteria (DUF2066). | 0.647 |
AGA86031.1 | AGA86030.1 | Psest_1477 | Psest_1476 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | Putative permease; PFAM: Domain of unknown function DUF20. | 0.801 |
AGA86031.1 | AGA88040.1 | Psest_1477 | Psest_3551 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.671 |
AGA86031.1 | dnaA | Psest_1477 | Psest_0002 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.594 |
AGA86031.1 | gmhA | Psest_1477 | Psest_3273 | PFAM: Bacterial dnaA protein; TIGRFAM: DnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.598 |