node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGA86754.1 | AGA86846.1 | Psest_2220 | Psest_2320 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | 0.973 |
AGA86754.1 | acsA | Psest_2220 | Psest_2657 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.917 |
AGA86754.1 | glcB | Psest_2220 | Psest_0354 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.947 |
AGA86754.1 | glcB-2 | Psest_2220 | Psest_3837 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.947 |
AGA86754.1 | prpB | Psest_2220 | Psest_2321 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.890 |
AGA86754.1 | sucC | Psest_2220 | Psest_2491 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.884 |
AGA86754.1 | sucD | Psest_2220 | Psest_2490 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.873 |
AGA86835.1 | AGA86844.1 | Psest_2309 | Psest_2318 | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 2-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. | 0.924 |
AGA86835.1 | AGA86846.1 | Psest_2309 | Psest_2320 | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | 0.909 |
AGA86835.1 | prpB | Psest_2309 | Psest_2321 | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.920 |
AGA86835.1 | sucC | Psest_2309 | Psest_2491 | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.881 |
AGA86835.1 | sucD | Psest_2309 | Psest_2490 | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.516 |
AGA86844.1 | AGA86835.1 | Psest_2318 | Psest_2309 | 2-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 0.924 |
AGA86844.1 | AGA86846.1 | Psest_2318 | Psest_2320 | 2-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | 0.931 |
AGA86844.1 | AGA86848.1 | Psest_2318 | Psest_2322 | 2-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. | PFAM: Bacterial regulatory proteins, gntR family; FCD domain. | 0.600 |
AGA86844.1 | prpB | Psest_2318 | Psest_2321 | 2-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.886 |
AGA86846.1 | AGA86754.1 | Psest_2320 | Psest_2220 | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. | 0.973 |
AGA86846.1 | AGA86835.1 | Psest_2320 | Psest_2309 | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 0.909 |
AGA86846.1 | AGA86844.1 | Psest_2320 | Psest_2318 | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | 2-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. | 0.931 |
AGA86846.1 | AGA86848.1 | Psest_2320 | Psest_2322 | PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. | PFAM: Bacterial regulatory proteins, gntR family; FCD domain. | 0.633 |