node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_3581 | cmk | Psyr_3581 | Psyr_3643 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | Cytidylate kinase. | 0.674 |
Psyr_3581 | der | Psyr_3581 | Psyr_1252 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.813 |
Psyr_4815 | der | Psyr_4815 | Psyr_1252 | Small GTP-binding protein domain:GTP-binding protein TypA. | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.762 |
Psyr_4815 | obg | Psyr_4815 | Psyr_0703 | Small GTP-binding protein domain:GTP-binding protein TypA. | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.458 |
cmk | Psyr_3581 | Psyr_3643 | Psyr_3581 | Cytidylate kinase. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.674 |
cmk | der | Psyr_3643 | Psyr_1252 | Cytidylate kinase. | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.988 |
cmk | ffh | Psyr_3643 | Psyr_1281 | Cytidylate kinase. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | 0.738 |
cmk | ftsY | Psyr_3643 | Psyr_4751 | Cytidylate kinase. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.591 |
cmk | gpsA | Psyr_3643 | Psyr_2022 | Cytidylate kinase. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.543 |
der | Psyr_3581 | Psyr_1252 | Psyr_3581 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.813 |
der | Psyr_4815 | Psyr_1252 | Psyr_4815 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Small GTP-binding protein domain:GTP-binding protein TypA. | 0.762 |
der | cmk | Psyr_1252 | Psyr_3643 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Cytidylate kinase. | 0.988 |
der | dnaG | Psyr_1252 | Psyr_4640 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.890 |
der | engB | Psyr_1252 | Psyr_0269 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Cell division checkpoint GTPase YihA; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.902 |
der | ffh | Psyr_1252 | Psyr_1281 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | 0.776 |
der | ftsY | Psyr_1252 | Psyr_4751 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.748 |
der | gpsA | Psyr_1252 | Psyr_2022 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.928 |
der | hflX | Psyr_1252 | Psyr_0573 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.828 |
der | obg | Psyr_1252 | Psyr_0703 | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.880 |
dnaG | der | Psyr_4640 | Psyr_1252 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Small GTP-binding protein protein domain:GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.890 |