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maeA maeA Psyr_4031 Psyr_4031 fumC fumC Psyr_5060 Psyr_5060 Psyr_4029 Psyr_4029 Psyr_2314 Psyr_2314 Psyr_5061 Psyr_5061 glcB glcB Psyr_2090 Psyr_2090 lldD lldD mqo mqo
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maeANAD-dependent malic enzyme; Belongs to the malic enzymes family. (573 aa)    
Predicted Functional Partners:
Psyr_4031
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.957
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.943
Psyr_5060
Oxaloacetate decarboxylase, alpha subunit.
    
 0.940
Psyr_4029
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.938
Psyr_2314
Pyruvate dehydrogenase (cytochrome); Belongs to the TPP enzyme family.
  
 
 0.918
Psyr_5061
acetyl-CoA carboxylase carboxyltransferase subunit alpha / biotin carboxylase.
   
 0.917
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.916
Psyr_2090
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.912
lldD
FMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
    
 0.911
mqo
Malate:quinone-oxidoreductase.
    
 0.910
Your Current Organism:
Pseudomonas syringae B728a
NCBI taxonomy Id: 205918
Other names: P. syringae pv. syringae B728a, Pseudomonas syringae pv. syringae B728a, Pseudomonas syringae pv. syringae str. B728a, Pseudomonas syringae pv. syringae strain B728a
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