node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_0002 | Psyr_2361 | Psyr_0002 | Psyr_2361 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA damage-inducible DNA polymerase II. | 0.977 |
Psyr_0002 | Psyr_2522 | Psyr_0002 | Psyr_2522 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conserved hypothetical protein. | 0.704 |
Psyr_0002 | dnaE2 | Psyr_0002 | Psyr_2523 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.793 |
Psyr_0002 | polA | Psyr_0002 | Psyr_0270 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
Psyr_0002 | recA | Psyr_0002 | Psyr_1378 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.817 |
Psyr_2361 | Psyr_0002 | Psyr_2361 | Psyr_0002 | DNA damage-inducible DNA polymerase II. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.977 |
Psyr_2361 | Psyr_2522 | Psyr_2361 | Psyr_2522 | DNA damage-inducible DNA polymerase II. | Conserved hypothetical protein. | 0.684 |
Psyr_2361 | polA | Psyr_2361 | Psyr_0270 | DNA damage-inducible DNA polymerase II. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.976 |
Psyr_2361 | recA | Psyr_2361 | Psyr_1378 | DNA damage-inducible DNA polymerase II. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.736 |
Psyr_2519 | Psyr_2521 | Psyr_2519 | Psyr_2521 | Aldo/keto reductase. | Conserved hypothetical protein. | 0.496 |
Psyr_2519 | Psyr_2522 | Psyr_2519 | Psyr_2522 | Aldo/keto reductase. | Conserved hypothetical protein. | 0.518 |
Psyr_2519 | Psyr_2524 | Psyr_2519 | Psyr_2524 | Aldo/keto reductase. | Conserved hypothetical protein. | 0.490 |
Psyr_2519 | dnaE2 | Psyr_2519 | Psyr_2523 | Aldo/keto reductase. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.490 |
Psyr_2519 | lexA | Psyr_2519 | Psyr_2520 | Aldo/keto reductase. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.491 |
Psyr_2521 | Psyr_2519 | Psyr_2521 | Psyr_2519 | Conserved hypothetical protein. | Aldo/keto reductase. | 0.496 |
Psyr_2521 | Psyr_2522 | Psyr_2521 | Psyr_2522 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.994 |
Psyr_2521 | Psyr_2524 | Psyr_2521 | Psyr_2524 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.774 |
Psyr_2521 | dnaE2 | Psyr_2521 | Psyr_2523 | Conserved hypothetical protein. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.968 |
Psyr_2521 | lexA | Psyr_2521 | Psyr_2520 | Conserved hypothetical protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.864 |
Psyr_2521 | lexA-2 | Psyr_2521 | Psyr_3283 | Conserved hypothetical protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.486 |