node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_1352 | Psyr_3282 | Psyr_1352 | Psyr_3282 | Outer membrane protein (OmpH-like). | Transcriptional regulator, TetR family. | 0.488 |
Psyr_1352 | Psyr_3284 | Psyr_1352 | Psyr_3284 | Outer membrane protein (OmpH-like). | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.400 |
Psyr_1352 | Psyr_4019 | Psyr_1352 | Psyr_4019 | Outer membrane protein (OmpH-like). | H-NS family protein MvaT. | 0.743 |
Psyr_3280 | Psyr_3282 | Psyr_3280 | Psyr_3282 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Transcriptional regulator, TetR family. | 0.547 |
Psyr_3280 | nagZ | Psyr_3280 | Psyr_3281 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Glycoside hydrolase, family 3, N-terminal; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.798 |
Psyr_3282 | Psyr_1352 | Psyr_3282 | Psyr_1352 | Transcriptional regulator, TetR family. | Outer membrane protein (OmpH-like). | 0.488 |
Psyr_3282 | Psyr_3280 | Psyr_3282 | Psyr_3280 | Transcriptional regulator, TetR family. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.547 |
Psyr_3282 | Psyr_3284 | Psyr_3282 | Psyr_3284 | Transcriptional regulator, TetR family. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.497 |
Psyr_3282 | Psyr_3420 | Psyr_3282 | Psyr_3420 | Transcriptional regulator, TetR family. | Conserved hypothetical protein. | 0.443 |
Psyr_3282 | Psyr_4019 | Psyr_3282 | Psyr_4019 | Transcriptional regulator, TetR family. | H-NS family protein MvaT. | 0.404 |
Psyr_3282 | lexA-2 | Psyr_3282 | Psyr_3283 | Transcriptional regulator, TetR family. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.519 |
Psyr_3282 | nagZ | Psyr_3282 | Psyr_3281 | Transcriptional regulator, TetR family. | Glycoside hydrolase, family 3, N-terminal; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.548 |
Psyr_3284 | Psyr_1352 | Psyr_3284 | Psyr_1352 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Outer membrane protein (OmpH-like). | 0.400 |
Psyr_3284 | Psyr_3282 | Psyr_3284 | Psyr_3282 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Transcriptional regulator, TetR family. | 0.497 |
Psyr_3284 | lexA-2 | Psyr_3284 | Psyr_3283 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.860 |
Psyr_3420 | Psyr_3282 | Psyr_3420 | Psyr_3282 | Conserved hypothetical protein. | Transcriptional regulator, TetR family. | 0.443 |
Psyr_4019 | Psyr_1352 | Psyr_4019 | Psyr_1352 | H-NS family protein MvaT. | Outer membrane protein (OmpH-like). | 0.743 |
Psyr_4019 | Psyr_3282 | Psyr_4019 | Psyr_3282 | H-NS family protein MvaT. | Transcriptional regulator, TetR family. | 0.404 |
lexA-2 | Psyr_3282 | Psyr_3283 | Psyr_3282 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Transcriptional regulator, TetR family. | 0.519 |
lexA-2 | Psyr_3284 | Psyr_3283 | Psyr_3284 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.860 |