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Psyr_3284 Psyr_3284 ftsZ ftsZ lexA-2 lexA-2 Psyr_4197 Psyr_4197 Psyr_1033 Psyr_1033 Psyr_3982 Psyr_3982 Psyr_2028 Psyr_2028 Psyr_0410 Psyr_0410 Psyr_4303 Psyr_4303 Psyr_4620 Psyr_4620 Psyr_1627 Psyr_1627
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Psyr_3284SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (156 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.878
lexA-2
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.860
Psyr_4197
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.811
Psyr_1033
YebG.
  
    0.800
Psyr_3982
3-hydroxyacyl-CoA-acyl carrier protein transferase.
  
   
 0.770
Psyr_2028
Conserved hypothetical protein.
  
     0.755
Psyr_0410
Conserved hypothetical protein.
  
     0.753
Psyr_4303
Protein of unknown function UPF0259.
  
     0.751
Psyr_4620
Conserved hypothetical protein.
  
     0.743
Psyr_1627
Conserved hypothetical protein.
  
     0.730
Your Current Organism:
Pseudomonas syringae B728a
NCBI taxonomy Id: 205918
Other names: P. syringae pv. syringae B728a, Pseudomonas syringae pv. syringae B728a, Pseudomonas syringae pv. syringae str. B728a, Pseudomonas syringae pv. syringae strain B728a
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