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hemL hemL Psyr_0292 Psyr_0292 hemA hemA hemC hemC Psyr_2611 Psyr_2611 Psyr_1957 Psyr_1957 Psyr_3927 Psyr_3927 cysG cysG thiE thiE Psyr_1794 Psyr_1794 Psyr_2098 Psyr_2098
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (427 aa)    
Predicted Functional Partners:
Psyr_0292
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.991
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.988
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.916
Psyr_2611
Amino acid adenylation; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.802
Psyr_1957
Amino acid adenylation.
  
 
 0.795
Psyr_3927
Siderophore-interacting protein.
     
 0.772
cysG
uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
   
 0.753
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.750
Psyr_1794
Amino acid adenylation.
 
 
 0.737
Psyr_2098
uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.725
Your Current Organism:
Pseudomonas syringae B728a
NCBI taxonomy Id: 205918
Other names: P. syringae pv. syringae B728a, Pseudomonas syringae pv. syringae B728a, Pseudomonas syringae pv. syringae str. B728a, Pseudomonas syringae pv. syringae strain B728a
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