node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
nadD | obg | Psyr_4368 | Psyr_0703 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.536 |
nadD | rlmH | Psyr_4368 | Psyr_4366 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.828 |
nadD | rsfS | Psyr_4368 | Psyr_4367 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.916 |
obg | nadD | Psyr_0703 | Psyr_4368 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.536 |
obg | rlmB | Psyr_0703 | Psyr_0580 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.688 |
obg | rplI | Psyr_0703 | Psyr_0584 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L9P; Binds to the 23S rRNA. | 0.768 |
obg | rplN | Psyr_0703 | Psyr_4538 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.649 |
obg | rplS | Psyr_0703 | Psyr_1285 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.870 |
obg | rplT | Psyr_0703 | Psyr_2165 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.951 |
obg | rplX | Psyr_0703 | Psyr_4537 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.796 |
obg | rpmF | Psyr_0703 | Psyr_1644 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family. | 0.805 |
obg | rsfS | Psyr_0703 | Psyr_4367 | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.894 |
rlmB | obg | Psyr_0580 | Psyr_0703 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | GTP-binding protein, HSR1-related:GTP1/OBG subdomain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.688 |
rlmB | rplI | Psyr_0580 | Psyr_0584 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | LSU ribosomal protein L9P; Binds to the 23S rRNA. | 0.637 |
rlmB | rplN | Psyr_0580 | Psyr_4538 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.729 |
rlmB | rplS | Psyr_0580 | Psyr_1285 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.543 |
rlmB | rplT | Psyr_0580 | Psyr_2165 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.674 |
rlmB | rplX | Psyr_0580 | Psyr_4537 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.798 |
rlmB | rpmF | Psyr_0580 | Psyr_1644 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | LSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family. | 0.431 |
rlmB | rsfS | Psyr_0580 | Psyr_4367 | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.850 |