STRINGSTRING
Fis Fis dusB dusB dusA dusA dusC dusC purH purH Psyr_1293 Psyr_1293 Psyr_1667 Psyr_1667 polA polA Psyr_2115 Psyr_2115 ihfA ihfA Psyr_3655 Psyr_3655
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FisDNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (106 aa)    
Predicted Functional Partners:
dusB
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
  
 0.968
dusA
tRNA-U16,U17-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
  
  
 0.651
dusC
tRNA-U20a,U20b-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
  
  
 0.651
purH
IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase.
  
    0.633
Psyr_1293
EAL:Response regulator receiver.
    
 
 0.619
Psyr_1667
Colicin V production protein.
  
     0.597
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.596
Psyr_2115
Response regulator receiver.
   
 
 0.574
ihfA
Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
      
 0.574
Psyr_3655
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).
    
 
 0.559
Your Current Organism:
Pseudomonas syringae B728a
NCBI taxonomy Id: 205918
Other names: P. syringae pv. syringae B728a, Pseudomonas syringae pv. syringae B728a, Pseudomonas syringae pv. syringae str. B728a, Pseudomonas syringae pv. syringae strain B728a
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.