node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_0221 | Psyr_4050 | Psyr_0221 | Psyr_4050 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Protein of unknown function DUF479. | 0.900 |
Psyr_0221 | RibC | Psyr_0221 | Psyr_0709 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | 0.667 |
Psyr_0221 | coaD | Psyr_0221 | Psyr_4758 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.945 |
Psyr_0221 | coaE | Psyr_0221 | Psyr_0795 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.624 |
Psyr_0221 | coaX | Psyr_0221 | Psyr_4563 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.929 |
Psyr_0221 | guaA | Psyr_0221 | Psyr_1262 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.401 |
Psyr_4050 | Psyr_0221 | Psyr_4050 | Psyr_0221 | Protein of unknown function DUF479. | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
Psyr_4050 | coaD | Psyr_4050 | Psyr_4758 | Protein of unknown function DUF479. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.904 |
Psyr_4050 | coaX | Psyr_4050 | Psyr_4563 | Protein of unknown function DUF479. | Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.917 |
Psyr_4754 | cmk | Psyr_4754 | Psyr_3643 | 16S rRNA m(2)G-966 methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Cytidylate kinase. | 0.578 |
Psyr_4754 | coaD | Psyr_4754 | Psyr_4758 | 16S rRNA m(2)G-966 methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.758 |
Psyr_4754 | pyrH | Psyr_4754 | Psyr_1345 | 16S rRNA m(2)G-966 methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.424 |
Psyr_4759 | coaD | Psyr_4759 | Psyr_4758 | 4Fe-4S ferredoxin, iron-sulfur binding protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.611 |
RibC | Psyr_0221 | Psyr_0709 | Psyr_0221 | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.667 |
RibC | cmk | Psyr_0709 | Psyr_3643 | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | Cytidylate kinase. | 0.797 |
RibC | coaD | Psyr_0709 | Psyr_4758 | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.677 |
RibC | coaE | Psyr_0709 | Psyr_0795 | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.530 |
RibC | guaA | Psyr_0709 | Psyr_1262 | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.485 |
RibC | pyrH | Psyr_0709 | Psyr_1345 | FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.553 |
cmk | Psyr_4754 | Psyr_3643 | Psyr_4754 | Cytidylate kinase. | 16S rRNA m(2)G-966 methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.578 |