node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_2139 | Psyr_4950 | Psyr_2139 | Psyr_4950 | Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Peptidase M48, Ste24p. | 0.423 |
Psyr_2139 | ftsH | Psyr_2139 | Psyr_4187 | Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.445 |
Psyr_4950 | Psyr_2139 | Psyr_4950 | Psyr_2139 | Peptidase M48, Ste24p. | Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.423 |
Psyr_4950 | Psyr_4951 | Psyr_4950 | Psyr_4951 | Peptidase M48, Ste24p. | Hypothetical protein. | 0.773 |
Psyr_4950 | Psyr_4958 | Psyr_4950 | Psyr_4958 | Peptidase M48, Ste24p. | AAA ATPase, central region:Clp, N terminal:Clp, N terminal; Belongs to the ClpA/ClpB family. | 0.455 |
Psyr_4950 | ftsH | Psyr_4950 | Psyr_4187 | Peptidase M48, Ste24p. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.464 |
Psyr_4950 | grpE | Psyr_4950 | Psyr_4196 | Peptidase M48, Ste24p. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.522 |
Psyr_4951 | Psyr_4950 | Psyr_4951 | Psyr_4950 | Hypothetical protein. | Peptidase M48, Ste24p. | 0.773 |
Psyr_4958 | Psyr_4950 | Psyr_4958 | Psyr_4950 | AAA ATPase, central region:Clp, N terminal:Clp, N terminal; Belongs to the ClpA/ClpB family. | Peptidase M48, Ste24p. | 0.455 |
Psyr_4958 | grpE | Psyr_4958 | Psyr_4196 | AAA ATPase, central region:Clp, N terminal:Clp, N terminal; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.731 |
ftsH | Psyr_2139 | Psyr_4187 | Psyr_2139 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.445 |
ftsH | Psyr_4950 | Psyr_4187 | Psyr_4950 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Peptidase M48, Ste24p. | 0.464 |
ftsH | grpE | Psyr_4187 | Psyr_4196 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.666 |
grpE | Psyr_4950 | Psyr_4196 | Psyr_4950 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Peptidase M48, Ste24p. | 0.522 |
grpE | Psyr_4958 | Psyr_4196 | Psyr_4958 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | AAA ATPase, central region:Clp, N terminal:Clp, N terminal; Belongs to the ClpA/ClpB family. | 0.731 |
grpE | ftsH | Psyr_4196 | Psyr_4187 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.666 |