node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_3645 | Psyr_5027 | Psyr_3645 | Psyr_5027 | Prephenate dehydratase. | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.506 |
Psyr_3645 | ihfA | Psyr_3645 | Psyr_2168 | Prephenate dehydratase. | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.506 |
Psyr_3645 | rpsO | Psyr_3645 | Psyr_4177 | Prephenate dehydratase. | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.547 |
Psyr_3645 | rpsT | Psyr_3645 | Psyr_0707 | Prephenate dehydratase. | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. | 0.433 |
Psyr_5026 | Psyr_5027 | Psyr_5026 | Psyr_5027 | Conserved hypothetical protein. | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.435 |
Psyr_5027 | Psyr_3645 | Psyr_5027 | Psyr_3645 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Prephenate dehydratase. | 0.506 |
Psyr_5027 | Psyr_5026 | Psyr_5027 | Psyr_5026 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Conserved hypothetical protein. | 0.435 |
Psyr_5027 | Psyr_5028 | Psyr_5027 | Psyr_5028 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Belongs to the FAD-dependent oxidoreductase family. | 0.509 |
Psyr_5027 | dnaA | Psyr_5027 | Psyr_0001 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.451 |
Psyr_5027 | ihfA | Psyr_5027 | Psyr_2168 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.565 |
Psyr_5027 | polA | Psyr_5027 | Psyr_0270 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.489 |
Psyr_5027 | rplL | Psyr_5027 | Psyr_4556 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.436 |
Psyr_5027 | rpsO | Psyr_5027 | Psyr_4177 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.548 |
Psyr_5027 | rpsT | Psyr_5027 | Psyr_0707 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. | 0.442 |
Psyr_5027 | topA | Psyr_5027 | Psyr_3287 | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.431 |
Psyr_5028 | Psyr_5027 | Psyr_5028 | Psyr_5027 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Belongs to the FAD-dependent oxidoreductase family. | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.509 |
dnaA | Psyr_5027 | Psyr_0001 | Psyr_5027 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Bacterial nucleoid protein HU alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.451 |
dnaA | ihfA | Psyr_0001 | Psyr_2168 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.459 |
dnaA | polA | Psyr_0001 | Psyr_0270 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.574 |
dnaA | topA | Psyr_0001 | Psyr_3287 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.502 |