Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apn1 | apn2 | P50525 | P87175 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | 0.998 |
| apn1 | mag1 | P50525 | Q92383 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | DNA-3-methyladenine glycosylase 1; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. Can release ethylated and propylated bases from DNA in addition to 3-methyladenine; Belongs to the alkylbase DNA glycosidase AlkA family. | 0.594 |
| apn1 | mag2 | P50525 | O94468 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | Probable DNA-3-methyladenine glycosylase 2; Involved in base excision repair of methyl methanesulfonate- damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. | 0.591 |
| apn1 | myh1 | P50525 | Q10159 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. Has glycosylase and nicking activities and is active at A/G and A/GO sites. | 0.804 |
| apn1 | nth1 | P50525 | Q09907 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8- dihydroguanine (8-oxoG) DNA glycosylas [...] | 0.959 |
| apn1 | thp1 | P50525 | O59825 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | G/U mismatch-specific uracil DNA glycosylase; Removes uracil from G/U mispairs in ssDNA. Also corrects G/G mispairs. Does not catalyze the removal of thymine from G/T mispairs. | 0.492 |
| apn1 | ung1 | P50525 | O74834 | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.930 |
| apn2 | apn1 | P87175 | P50525 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1. | 0.998 |
| apn2 | hus1 | P87175 | P78955 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Checkpoint protein hus1; Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication. It is also required for the response to DNA damage. | 0.614 |
| apn2 | mag1 | P87175 | Q92383 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA-3-methyladenine glycosylase 1; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. Can release ethylated and propylated bases from DNA in addition to 3-methyladenine; Belongs to the alkylbase DNA glycosidase AlkA family. | 0.810 |
| apn2 | mag2 | P87175 | O94468 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Probable DNA-3-methyladenine glycosylase 2; Involved in base excision repair of methyl methanesulfonate- damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. | 0.766 |
| apn2 | myh1 | P87175 | Q10159 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. Has glycosylase and nicking activities and is active at A/G and A/GO sites. | 0.882 |
| apn2 | nth1 | P87175 | Q09907 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8- dihydroguanine (8-oxoG) DNA glycosylas [...] | 0.986 |
| apn2 | thp1 | P87175 | O59825 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | G/U mismatch-specific uracil DNA glycosylase; Removes uracil from G/U mispairs in ssDNA. Also corrects G/G mispairs. Does not catalyze the removal of thymine from G/T mispairs. | 0.694 |
| apn2 | ung1 | P87175 | O74834 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.910 |
| ast1 | myh1 | O14061 | Q10159 | Asteroid homolog 1. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. Has glycosylase and nicking activities and is active at A/G and A/GO sites. | 0.756 |
| hus1 | apn2 | P78955 | P87175 | Checkpoint protein hus1; Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication. It is also required for the response to DNA damage. | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | 0.614 |
| hus1 | myh1 | P78955 | Q10159 | Checkpoint protein hus1; Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication. It is also required for the response to DNA damage. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. Has glycosylase and nicking activities and is active at A/G and A/GO sites. | 0.883 |
| hus1 | nth1 | P78955 | Q09907 | Checkpoint protein hus1; Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication. It is also required for the response to DNA damage. | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8- dihydroguanine (8-oxoG) DNA glycosylas [...] | 0.434 |
| hus1 | rad1 | P78955 | P22193 | Checkpoint protein hus1; Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication. It is also required for the response to DNA damage. | DNA damage checkpoint control protein rad1; Recombinational reparation of DNA damages induced by UV and gamma radiation. | 0.999 |
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