STRINGSTRING
K02F3.12 K02F3.12 tag-51 tag-51 pign-1 pign-1 exos-4.2 exos-4.2 arx-4 arx-4 arx-7 arx-7 guk-1 guk-1 exo-1 exo-1 dna-2 dna-2 C26D10.3 C26D10.3 cku-70 cku-70
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K02F3.12Putative ATP-dependent DNA helicase Q1; DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Belongs to the helicase family. RecQ subfamily. (631 aa)    
Predicted Functional Partners:
tag-51
Uncharacterized protein tag-51.
   
  
 0.910
pign-1
PigN domain-containing protein.
   
  
 0.854
exos-4.2
RNase_PH domain-containing protein.
      
 0.853
arx-4
Probable actin-related protein 2/3 complex subunit 2; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity).
      
 0.807
arx-7
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
      
 0.698
guk-1
Guanylate kinase-like domain-containing protein.
 
  
 
 0.673
exo-1
EXOnuclease.
  
 
 0.609
dna-2
Yeast DNA helicase/endonuclease family.
   
  
 0.560
C26D10.3
Uncharacterized protein.
     
 0.542
cku-70
Ku domain-containing protein.
   
 
 0.539
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (30%) [HD]