Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adl1 | apn2 | Q9C1W9 | P87175 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | 0.715 |
| adl1 | hnt3 | Q9C1W9 | O74859 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | Aprataxin-like protein; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'- phosphate termini that can be efficiently rejoined. Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, bu [...] | 0.810 |
| adl1 | lig4 | Q9C1W9 | O74833 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | DNA ligase 4; Involved in ds DNA break repair. Belongs to the ATP-dependent DNA ligase family. | 0.536 |
| adl1 | pnk1 | Q9C1W9 | O13911 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | Bifunctional polynucleotide phosphatase/kinase; Catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. Has a role in the repair of breaks in single-stranded DNA; In the N-terminal section; belongs to the DNA 3' phosphatase family. | 0.634 |
| adl1 | swi10 | Q9C1W9 | Q06182 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | Mating-type switching protein swi10; Involved in termination of copy-synthesis during mating-type switching. Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD16 forms an endonuclease that specifically degrades single-stranded DNA; Belongs to the ERCC1/RAD10/SWI10 family. | 0.429 |
| adl1 | tdp1 | Q9C1W9 | Q9USG9 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | Probable tyrosyl-DNA phosphodiesterase; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead- end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. May have low 3'exonuclease activity and may be able to remove a sin [...] | 0.862 |
| adl1 | top1 | Q9C1W9 | P07799 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. TThe free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus rem [...] | 0.549 |
| adl1 | top2 | Q9C1W9 | P08096 | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.452 |
| apn2 | adl1 | P87175 | Q9C1W9 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | 0.715 |
| apn2 | hnt3 | P87175 | O74859 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Aprataxin-like protein; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'- phosphate termini that can be efficiently rejoined. Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, bu [...] | 0.734 |
| apn2 | lig4 | P87175 | O74833 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA ligase 4; Involved in ds DNA break repair. Belongs to the ATP-dependent DNA ligase family. | 0.438 |
| apn2 | mus81 | P87175 | P87231 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI). Belongs to the XPF family. | 0.579 |
| apn2 | pnk1 | P87175 | O13911 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Bifunctional polynucleotide phosphatase/kinase; Catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. Has a role in the repair of breaks in single-stranded DNA; In the N-terminal section; belongs to the DNA 3' phosphatase family. | 0.927 |
| apn2 | rad16 | P87175 | P36617 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA repair protein rad16; Endonuclease that specifically degrades single-stranded DNA and which is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Required for double strand break-induced interchromosomal gene conversion. Belongs to the XPF family. | 0.909 |
| apn2 | swi10 | P87175 | Q06182 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Mating-type switching protein swi10; Involved in termination of copy-synthesis during mating-type switching. Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD16 forms an endonuclease that specifically degrades single-stranded DNA; Belongs to the ERCC1/RAD10/SWI10 family. | 0.722 |
| apn2 | tdp1 | P87175 | Q9USG9 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | Probable tyrosyl-DNA phosphodiesterase; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead- end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. May have low 3'exonuclease activity and may be able to remove a sin [...] | 0.947 |
| apn2 | top1 | P87175 | P07799 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. TThe free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus rem [...] | 0.750 |
| apn2 | top2 | P87175 | P08096 | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.580 |
| hnt3 | adl1 | O74859 | Q9C1W9 | Aprataxin-like protein; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'- phosphate termini that can be efficiently rejoined. Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, bu [...] | DNA ligase 3; Belongs to the ATP-dependent DNA ligase family. | 0.810 |
| hnt3 | apn2 | O74859 | P87175 | Aprataxin-like protein; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'- phosphate termini that can be efficiently rejoined. Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, bu [...] | DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides the majority of the AP-endonuclease (APE) activity. Repairs phleomycin D1-induced DNA damage. Plays a role in oxidative damage repair; Belongs to the DNA repair enzymes AP/ExoA family. | 0.734 |
page 1 of 5