STRINGSTRING
DSS1(I) DSS1(I) BRCA2B BRCA2B BRCA2A BRCA2A RPN3B RPN3B RPN3A RPN3A RPN7 RPN7 RPN6 RPN6 SAC3C SAC3C SAC3B SAC3B RPN10 RPN10 SAC3A SAC3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSS1(I)Protein DELETION OF SUV3 SUPPRESSOR 1(I); Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family. (74 aa)    
Predicted Functional Partners:
BRCA2B
Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B; Involved in double-strand break repair and/or homologous recombination by mediating RAD51- and DMC1-facilitated DNA repair. Plays an essential role in both somatic and meiotic homologous recombination. Is crucial for the formation of RAD51 and DMC1 foci during male meiotic homologous recombination in prophase I.
    
 0.997
BRCA2A
Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A; Involved in double-strand break repair and/or homologous recombination by mediating RAD51- and DMC1-facilitated DNA repair. Plays an essential role in both somatic and meiotic homologous recombination. Is crucial for the formation of RAD51 and DMC1 foci during male meiotic homologous recombination in prophase I.
    
 0.997
RPN3B
26S proteasome non-ATPase regulatory subunit 3 homolog B; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.994
RPN3A
26S proteasome non-ATPase regulatory subunit 3 homolog A; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.991
RPN7
26S proteasome non-ATPase regulatory subunit 6 homolog; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 
 0.988
RPN6
26S proteasome non-ATPase regulatory subunit 11 homolog; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6A is required for proteasome assembly (By similarity).
    
 0.986
SAC3C
SAC3 family protein C; Possible component of the TREX-2 complex (transcription and export complex 2), a muliprotein complex that functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
   
 
 0.982
SAC3B
SAC3 family protein B; Component of the TREX-2 complex (transcription and export complex 2), a muliprotein complex that functions in docking export- competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Belongs to the SAC3 family.
    
 
 0.979
RPN10
26S proteasome non-ATPase regulatory subunit 4 homolog; Plays a role in maintaining the structural integrity of the 19S regulatory particle (RP), subcomplex of the 26S proteasome. Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a potential docking subunit for both ubiquitin receptors RAD23s and [...]
   
 0.971
SAC3A
SAC3 family protein A; Component of the TREX-2 complex (transcription and export complex 2), a muliprotein complex that functions in docking export- competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
    
 
 0.966
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.