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There are several matches for 'RNA_10'.
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2476 matches
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organism
protein
1)
Homo sapiens
RBM10 -
RNA
-binding protein
10
; May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to
RNA
homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins.
[a.k.a. CCDS14274, ENST00000333242, BAA09471.1]
2)
Homo sapiens
MED10 - Mediator of
RNA
polymerase II transcription subunit
10
; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors.
[a.k.a. MED10_HUMAN, R-HSA-556833, ENST00000503112.1]
3)
Homo sapiens
EXOSC10 - Exosome component
10
; Putative catalytic component of the
RNA
exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular
RNA
processing and degradation events. In the nucleus, the
RNA
exosome complex is involved in proper maturation of stable
RNA
species such as rRNA, snRNA and snoRNA, in the elimination of
RNA
processing by-products and non-coding 'pervasive' transcripts, such as antisense
RNA
species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...]
[a.k.a. ENST00000485606, 3SAF, EXOSC10-208]
4)
Homo sapiens
DDX5 - Probable ATP-dependent
RNA
helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its
RNA
helicase activity is necessary for increasing tau exon
10
inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon
10
. The rate of ATP hydrolysis is highly stimulated by single-stranded
RNA
. Involved in transcriptional regulation; the function is independent of the
RNA
helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1
RNA
to activate MYOD1 t [...]
[a.k.a. DDX5-206, ENSP00000225792, ENST00000583894.1]
5)
Homo sapiens
DCPS - m7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to
10
nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated
RNA
fragments and 7- methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not h [...]
[a.k.a. HSL1, AAH14532.1, HSPC015]
6)
Homo sapiens
DDX11 - ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and heterochromatin organization as well as in ribosomal
RNA
synthesis. Its double-stranded DNA helicase activity requires either a minimal 5'-single-stranded tail length of approximately 15 nt (flap substrates) or
10
nt length single- stranded gapped DNA substrates of a partial duplex DNA structure for helicase loading and translocation along DNA in a 5' to 3' direction. The helicase activity is capable [...]
[a.k.a. ENST00000539699, DDX11-218, ENST00000545115]
7)
Homo sapiens
TRA2B - Transformer-2 protein homolog beta; Sequence-specific
RNA
-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon
10
. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7
RNA
. Binds to pre-mRNA. Belongs to the splicing factor SR family.
[a.k.a. ENST00000342294, URS0000D6D87F, P62995]
8)
Homo sapiens
SFSWAP - Splicing factor, suppressor of white-apricot homolog; Plays a role as an alternative splicing regulator. Regulate its own expression at the level of
RNA
processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon
10
.
[a.k.a. U08377, NP_001248340.1, XP_011536957.1]
9)
Homo sapiens
SRSF7 - Serine/arginine-rich splicing factor 7; Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon
10
. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1- NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1
RNA
- binding activity.
RNA
-binding is semi-sequence specific.
[a.k.a. 9G8, ENST00000378857, SFRS7]
10)
Homo sapiens
INTS10 - Integrator complex subunit
10
; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of
RNA
polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.
[a.k.a. AK001431, FLJ10569, chromosome 8 open reading frame 35]
11)
Homo sapiens
PTBP1 - Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote
RNA
looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon
10
. In case of infection by picorn [...]
[a.k.a. PTBP1-219, Q9BUQ0, ENSP00000322596]
12)
Homo sapiens
CELF3 - CUGBP Elav-like family member 3;
RNA
-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon
10
. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
[a.k.a. XM_006711139, ENSP00000290585, ERDA4]
13)
Homo sapiens
SRSF10 - Serine/arginine-rich splicing factor
10
; Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing. Interaction with YTHDC1, a
RNA
-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, lead [...]
[a.k.a. URS0000D43731, NP_001177934.1, NP_001177936.1]
14)
Homo sapiens
CELF4 - CUGBP Elav-like family member 4;
RNA
-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon
10
. Binds to muscle-specific splicing enhancer (MSE) intronic site [...]
[a.k.a. ENSP00000406823, NM_001353718, Q9BZC1]
15)
Mus musculus
Rbm10 -
RNA
-binding protein
10
; Not known. Binds to
RNA
homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins (By similarity).
[a.k.a. Rbm10-206, NM_001167775.1, MGI:2384310]
16)
Mus musculus
Med10 - Mediator of
RNA
polymerase II transcription subunit
10
; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors (By similarity).
[a.k.a. ENSMUST00000223376, 28077, Q9CXU0]
17)
Mus musculus
Exosc10 - Exosome component
10
; Putative catalytic component of the
RNA
exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular
RNA
processing and degradation events. In the nucleus, the
RNA
exosome complex is involved in proper maturation of stable
RNA
species such as rRNA, snRNA and snoRNA, in the elimination of
RNA
processing by-products and non-coding 'pervasive' transcripts, such as antisense
RNA
species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...]
[a.k.a. AF092082, 50912, ENSMUST00000017408]
18)
Mus musculus
Ddx5 - Probable ATP-dependent
RNA
helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its
RNA
helicase activity is necessary for increasing tau exon
10
inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon
10
. The rate of ATP hydrolysis is highly stimulated by single-stranded
RNA
. Involved in transcriptional regulation; the function is independent of the
RNA
helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1
RNA
to activate MYOD1 t [...]
[a.k.a. UPI000003B457, Ddx5-203, ENSMUSP00000138184]
19)
Mus musculus
Dcps - m7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to
10
nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated
RNA
fragments and 7- methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not h [...]
[a.k.a. NP_081306.1, R-MMU-429914, AC140448]
20)
Mus musculus
Ddx11 - ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and heterochromatin organization as well as in ribosomal
RNA
synthesis. Its double-stranded DNA helicase activity requires either a minimal 5'-single-stranded tail length of approximately 15 nt (flap substrates) or
10
nt length single-stranded gapped DNA substrates of a partial duplex DNA structure for helicase loading and translocation along DNA in a 5' to 3' direction. The helicase activity is capable [...]
[a.k.a. NP_001335221.1, UPI00001E3C37, ENSMUST00000223600]
2476 matches
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