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There are several matches for 'RNA_12'.
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1164 matches
showing page 1 of 59
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organism
protein
1)
Homo sapiens
RRP12 - RRP12-like protein; Ribosomal
RNA
processing
12
homolog.
[a.k.a. ENST00000622320, 23223, HPA074403]
2)
Homo sapiens
MED12 - Mediator of
RNA
polymerase II transcription subunit
12
; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors. This subunit may specifi [...]
[a.k.a. ENST00000429213, ENST00000333646.10, MED12-206]
3)
Homo sapiens
RBM12 -
RNA
binding motif protein
12
.
[a.k.a. NM_001198838.2, ENST00000424458, A6PVI0]
4)
Homo sapiens
MED12L - Mediator of
RNA
polymerase II transcription subunit
12
-like protein; May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors (By [...]
[a.k.a. Mediator complex subunit 12L, XM_017005681, Q96PC8]
5)
Homo sapiens
CDK12 - Cyclin-dependent kinase
12
; Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of
RNA
polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for
RNA
splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading [...]
[a.k.a. XP_016880236, XP_011523207, CDC2-related protein kinase 7]
6)
Homo sapiens
TAF12 - Transcription initiation factor TFIID subunit
12
; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of
RNA
polymerase transcription; Belongs to the TAF12 family.
[a.k.a. R-HSA-162587, R-HSA-73776, OTTHUMG00000003655]
7)
Homo sapiens
INTS12 - Integrator complex subunit
12
; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of
RNA
polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
[a.k.a. 57117, R-HSA-6807505, NM_020395]
8)
Homo sapiens
TTLL12 - Tubulin--tyrosine ligase-like protein
12
; Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During
RNA
virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
[a.k.a. NP_055955, V9GY16, AAH01070.1]
9)
Homo sapiens
NLRP12 - NACHT, LRR and PYD domains-containing protein
12
; Plays an essential role as an potent mitigator of inflammation. Primarily expressed in dendritic cells and macrophages, inhibits both canonical and non-canonical NF-kappa-B and ERK activation pathways. Functions as a negative regulator of NOD2 by targeting it to degradation via the proteasome pathway. In turn, promotes bacterial tolerance. Inhibits also the DDX58-mediated immune signaling against
RNA
viruses by reducing the E3 ubiquitin ligase TRIM25-mediated 'Lys-63'-linked DDX58 activation but enhancing the E3 ubiquitin ligase RNF125- [...]
[a.k.a. XP_016882949, XM_017027462, CCDS62784]
10)
Mus musculus
Rbm12 -
RNA
-binding protein
12
.
[a.k.a. BAB30825.1, 75710, ENSMUSP00000118067]
11)
Mus musculus
Med12 - Mediator of
RNA
polymerase II transcription subunit
12
; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors. This subunit may specifi [...]
[a.k.a. ENSMUSP00000112729, Q6PGD8, ENSMUST00000087948.10]
12)
Mus musculus
Med12l - Mediator of
RNA
polymerase II transcription subunit
12
-like protein; May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors (By [...]
[a.k.a. XP_017175107, MGI:2139916, NM_177855.3]
13)
Mus musculus
Cdk12 - Cyclin-dependent kinase
12
; Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of
RNA
polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for
RNA
splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading [...]
[a.k.a. CDC2-related protein kinase 7, XP_030102135, Crkrs]
14)
Mus musculus
Taf12 - Transcription initiation factor TFIID subunit
12
; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of
RNA
polymerase transcription (By similarity).
[a.k.a. XP_006539173.1, Taf12-203, XM_006539110.1]
15)
Mus musculus
Ints12 - Integrator complex subunit
12
; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of
RNA
polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
[a.k.a. ENSMUSP00000029650, Ints12-202, BC010657]
16)
Mus musculus
Ttll12 - Tubulin--tyrosine ligase-like protein
12
; Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During
RNA
virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE. Belongs to the tubulin--t [...]
[a.k.a. Tubulin tyrosine ligase-like family, member 12, R-MMU-392499, D430005B17]
17)
Mus musculus
Nlrp12 - NACHT, LRR and PYD domains-containing protein
12
; Plays an essential role as an potent mitigator of inflammation. Primarily expressed in dendritic cells and macrophages, inhibits both canonical and non- canonical NF-kappa-B and ERK activation pathways. Functions as a negative regulator of NOD2 by targeting it to degradation via the proteasome pathway. In turn, promotes bacterial tolerance. Inhibits also the DDX58-mediated immune signaling against
RNA
viruses by reducing the E3 ubiquitin ligase TRIM25-mediated 'Lys-63'-linked DDX58 activation but enhancing the E3 ubiquitin ligase RNF125 [...]
[a.k.a. LOC115489386, XM_017322321, Nlrp12-201]
18)
Drosophila melanogaster
kto - Mediator of
RNA
polymerase II transcription subunit
12
; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors. Required for leg and ey [...]
[a.k.a. FBgn0001324, kto-PB, kto-PA]
19)
Drosophila melanogaster
Cdk12 - Cyclin-dependent kinase
12
; Cyclin-dependent kinase which displays CTD kinase activity: hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest
RNA
polymerase II subunit, thereby acting as a key regulator of transcription elongation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
[a.k.a. FBgn0037093, Cdk12-PA, Cdk12-PC]
20)
Caenorhabditis elegans
dpy-22 - Mediator of
RNA
polymerase II transcription subunit
12
; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all
RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal
RNA
polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with
RNA
polymerase II and the general transcription factors (By similarity). Functio [...]
[a.k.a. F47A4.2, WBGene00001081, NP_509645]
1164 matches
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