STRINGSTRING
Rv0387c Rv0387c PPE9 PPE9 Rv2082 Rv2082 Rv2738c Rv2738c lysS lysS serS serS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Rv0387cRv0387c, (MTV036.22c), len: 244 aa. Conserved hypothetical protein, showing some similarity to MTCI237.20c, and M17282|HUMEL20_1 Human elastin gene, exon 1, Elastin (687 aa), FASTA scores: opt: 193, E(): 0.35,(34.4% identity in 189 aa overlap). (244 aa)    
Predicted Functional Partners:
PPE9
Rv0388c, (MTV036.23c), len: 180 aa. PPE9, Member of the Mycobacterium tuberculosis PPE family, highly similar to others e.g. MTCY10G2_10|Z92539 from Mycobacterium tuberculosis (391 aa), FASTA scores: opt: 667, E(): 0,(58.3% identity in 180 aa overlap) but much shorter.
 
  
 0.776
Rv2082
Rv2082, (MTCY49.21), len: 721 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis Rv0029, and to Rv3899c and Rv3900c which may be frameshifted.
   
  
 0.591
Rv2738c
Rv2738c, (MTV002.03c), len: 68 aa. Conserved hypothetical protein, equivalent to Q9CCC1|ML0986 hypothetical protein from Mycobacterium leprae (67 aa),FASTA scores: opt: 397, E(): 3.7e-22, (83.6% identity in 67 aa overlap). Also highly similar to O50484|SC4H8.05 hypothetical 7.5 KDA protein from Streptomyces coelicolor (64 aa), FASTA scores: opt: 185, E(): 5.9e-07, (39.7% identity in 63 aa overlap). Second part of the protein is highly similar to C-terminus of upstream ORF O33285|Rv2742c|MTV002.07c conserved hypothetical protein from Mycobacterium tuberculosis (277 aa), FASTA scores: op [...]
   
  
 0.520
lysS
Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase); Rv3598c, (MTCY07H7B.24), len: 505 aa. Probable lysS,lysyl-tRNA synthetase 1, equivalent to P46861|SYK_MYCLE|LYSS|ML0233 lysyl-tRNA synthetase from Mycobacterium leprae (507 aa), FASTA scores: opt: 2835,E(): 4.5e-172, (85.45% identity in 501 aa overlap); and similar with C-terminal part of Q9CC23|LYSX|ML1393 C-term lysyl-tRNA synthase from Mycobacterium leprae (1039 aa) FASTA scores: opt: 1257, E(): 7.6e-72, (44.55% identity in 505 aa overlap). Also similar to others e.g. P37477|SYK_BACSU|LYSS from Bacill [...]
      
 0.437
serS
SERYL-tRNA synthetase SerS (serine--tRNA ligase) (SERRS) (serine translase); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
   
  
 0.436
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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