node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0175 | Rv3491 | Rv0175 | Rv3491 | Rv0175, (MTCI28.15), len: 213 aa. Probable conserved Mce-associated membrane protein, equivalent, but longer in N-terminus, to CAC32127.1|AL583926 possible membrane protein from Mycobacterium leprae (182 aa). Also similar to mce-associated proteins from Mycobacterium tuberculosis e.g. Rv1363c, Rv0177, Rv1973, etc. Contains two 12 residue direct repeats at N-terminus. A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Unknown protein; Rv3491, (MTCY13E12.44), len: 192 aa. Unknown protein. No significant homology with other proteins. | 0.870 |
Rv0175 | lpqR | Rv0175 | Rv0838 | Rv0175, (MTCI28.15), len: 213 aa. Probable conserved Mce-associated membrane protein, equivalent, but longer in N-terminus, to CAC32127.1|AL583926 possible membrane protein from Mycobacterium leprae (182 aa). Also similar to mce-associated proteins from Mycobacterium tuberculosis e.g. Rv1363c, Rv0177, Rv1973, etc. Contains two 12 residue direct repeats at N-terminus. A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.550 |
Rv0315 | Rv3491 | Rv0315 | Rv3491 | Rv0315, (MTCY63.20), len: 294 aa. Possible beta-1,3-glucanase precursor (has hydrophobic stretch in its N-terminal part), similar to others e.g. Q51333|AAC44371.1 beta-1,3-glucanase II a from Oerskovia xanthineolytica (306 aa), FASTA scores: opt: 76, E(): 3e-14, (34.1% identity in 302 aa overlap); and AAC38290.1|AF052745 beta-1,3-glucanase II from Oerskovia xanthineolytica (435 aa). Contains glycosyl hydrolases family 16 active site signature (PS01034). | Unknown protein; Rv3491, (MTCY13E12.44), len: 192 aa. Unknown protein. No significant homology with other proteins. | 0.623 |
Rv0315 | lpqR | Rv0315 | Rv0838 | Rv0315, (MTCY63.20), len: 294 aa. Possible beta-1,3-glucanase precursor (has hydrophobic stretch in its N-terminal part), similar to others e.g. Q51333|AAC44371.1 beta-1,3-glucanase II a from Oerskovia xanthineolytica (306 aa), FASTA scores: opt: 76, E(): 3e-14, (34.1% identity in 302 aa overlap); and AAC38290.1|AF052745 beta-1,3-glucanase II from Oerskovia xanthineolytica (435 aa). Contains glycosyl hydrolases family 16 active site signature (PS01034). | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.665 |
Rv0839 | lpqR | Rv0839 | Rv0838 | Rv0839, (MTV043.32), len: 270 aa. Conserved hypothetical protein, similar to various hypothetical proteins or methyltransferases from yeast and bacteria e.g. T34740|SC1E6.19c|AL033505|SC1E6_19 hypothetical protein from Streptomyces coelicolor (273 aa), FASTA scores: opt: 1102, E(): 0, (58.6% identity in 263 aa overlap); T38024|Z98598|SPAC1B3.06c hypothetical protein from Schizosaccharomyces pombe (278 aa), FASTA scores: opt: 562,E(): 1.9e-3, (36.4% identity in 269 aa overlap); JC6531 avermectin B 5-O-methyltransferase from Streptomyces avermitilis (283 aa); etc. Also similar to other M [...] | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.781 |
Rv3491 | Rv0175 | Rv3491 | Rv0175 | Unknown protein; Rv3491, (MTCY13E12.44), len: 192 aa. Unknown protein. No significant homology with other proteins. | Rv0175, (MTCI28.15), len: 213 aa. Probable conserved Mce-associated membrane protein, equivalent, but longer in N-terminus, to CAC32127.1|AL583926 possible membrane protein from Mycobacterium leprae (182 aa). Also similar to mce-associated proteins from Mycobacterium tuberculosis e.g. Rv1363c, Rv0177, Rv1973, etc. Contains two 12 residue direct repeats at N-terminus. A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | 0.870 |
Rv3491 | Rv0315 | Rv3491 | Rv0315 | Unknown protein; Rv3491, (MTCY13E12.44), len: 192 aa. Unknown protein. No significant homology with other proteins. | Rv0315, (MTCY63.20), len: 294 aa. Possible beta-1,3-glucanase precursor (has hydrophobic stretch in its N-terminal part), similar to others e.g. Q51333|AAC44371.1 beta-1,3-glucanase II a from Oerskovia xanthineolytica (306 aa), FASTA scores: opt: 76, E(): 3e-14, (34.1% identity in 302 aa overlap); and AAC38290.1|AF052745 beta-1,3-glucanase II from Oerskovia xanthineolytica (435 aa). Contains glycosyl hydrolases family 16 active site signature (PS01034). | 0.623 |
Rv3491 | lpqR | Rv3491 | Rv0838 | Unknown protein; Rv3491, (MTCY13E12.44), len: 192 aa. Unknown protein. No significant homology with other proteins. | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.805 |
ddlA | lpqR | Rv2981c | Rv0838 | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.520 |
fadD16 | lpqR | Rv0852 | Rv0838 | Rv0852, (MTV043.45), len: 278 aa. Possible fadD16,fatty-acid-CoA synthetase, similar in part to various CoA ligases e.g. P18163|LCFB_RAT long-chain-fatty-acid--CoA ligase from Rattus norvegicus (Rat) (699 aa); D49366|LEP4CCOALA_1 4-coumarate:CoA ligase from Lithospermum erythrorhizon (636 aa), FASTA scores: opt: 134, E(): 0.15, (26.8% identity in 213 aa overlap); orgp|L09229|HUMFACAL_1 long-chain acyl-coenzyme A from homo sapiens (human) (699 aa), FASTA score: (50.0% identity in 40 aa overlap); etc. Contains PS00626 Regulator of chromosome condensation (RCC1) signature 2. | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.680 |
fadD16 | lprE | Rv0852 | Rv1252c | Rv0852, (MTV043.45), len: 278 aa. Possible fadD16,fatty-acid-CoA synthetase, similar in part to various CoA ligases e.g. P18163|LCFB_RAT long-chain-fatty-acid--CoA ligase from Rattus norvegicus (Rat) (699 aa); D49366|LEP4CCOALA_1 4-coumarate:CoA ligase from Lithospermum erythrorhizon (636 aa), FASTA scores: opt: 134, E(): 0.15, (26.8% identity in 213 aa overlap); orgp|L09229|HUMFACAL_1 long-chain acyl-coenzyme A from homo sapiens (human) (699 aa), FASTA score: (50.0% identity in 40 aa overlap); etc. Contains PS00626 Regulator of chromosome condensation (RCC1) signature 2. | Probable lipoprotein LprE; Rv1252c, (MTCY50.30), len: 202 aa. Probable lipoprotein lprE, some similarity to Mycobacterium tuberculosis protein Rv3483c|MTCY13E12.36C (220 aa), FASTA scores: E(): 7e-05, (29.5% identity in 200 aa overlap). Contains possible N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachment site (PS00013). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | 0.556 |
lpqI | lpqR | Rv0237 | Rv0838 | Probable conserved lipoprotein LpqI; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptidoglycan fragments. Acts as a regulator for GlcNAc-MurNAc levels by cleaving disaccharides and allowing the breakdown of MurNAc. | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.454 |
lpqR | Rv0175 | Rv0838 | Rv0175 | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Rv0175, (MTCI28.15), len: 213 aa. Probable conserved Mce-associated membrane protein, equivalent, but longer in N-terminus, to CAC32127.1|AL583926 possible membrane protein from Mycobacterium leprae (182 aa). Also similar to mce-associated proteins from Mycobacterium tuberculosis e.g. Rv1363c, Rv0177, Rv1973, etc. Contains two 12 residue direct repeats at N-terminus. A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | 0.550 |
lpqR | Rv0315 | Rv0838 | Rv0315 | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Rv0315, (MTCY63.20), len: 294 aa. Possible beta-1,3-glucanase precursor (has hydrophobic stretch in its N-terminal part), similar to others e.g. Q51333|AAC44371.1 beta-1,3-glucanase II a from Oerskovia xanthineolytica (306 aa), FASTA scores: opt: 76, E(): 3e-14, (34.1% identity in 302 aa overlap); and AAC38290.1|AF052745 beta-1,3-glucanase II from Oerskovia xanthineolytica (435 aa). Contains glycosyl hydrolases family 16 active site signature (PS01034). | 0.665 |
lpqR | Rv0839 | Rv0838 | Rv0839 | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Rv0839, (MTV043.32), len: 270 aa. Conserved hypothetical protein, similar to various hypothetical proteins or methyltransferases from yeast and bacteria e.g. T34740|SC1E6.19c|AL033505|SC1E6_19 hypothetical protein from Streptomyces coelicolor (273 aa), FASTA scores: opt: 1102, E(): 0, (58.6% identity in 263 aa overlap); T38024|Z98598|SPAC1B3.06c hypothetical protein from Schizosaccharomyces pombe (278 aa), FASTA scores: opt: 562,E(): 1.9e-3, (36.4% identity in 269 aa overlap); JC6531 avermectin B 5-O-methyltransferase from Streptomyces avermitilis (283 aa); etc. Also similar to other M [...] | 0.781 |
lpqR | Rv3491 | Rv0838 | Rv3491 | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Unknown protein; Rv3491, (MTCY13E12.44), len: 192 aa. Unknown protein. No significant homology with other proteins. | 0.805 |
lpqR | ddlA | Rv0838 | Rv2981c | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | 0.520 |
lpqR | fadD16 | Rv0838 | Rv0852 | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Rv0852, (MTV043.45), len: 278 aa. Possible fadD16,fatty-acid-CoA synthetase, similar in part to various CoA ligases e.g. P18163|LCFB_RAT long-chain-fatty-acid--CoA ligase from Rattus norvegicus (Rat) (699 aa); D49366|LEP4CCOALA_1 4-coumarate:CoA ligase from Lithospermum erythrorhizon (636 aa), FASTA scores: opt: 134, E(): 0.15, (26.8% identity in 213 aa overlap); orgp|L09229|HUMFACAL_1 long-chain acyl-coenzyme A from homo sapiens (human) (699 aa), FASTA score: (50.0% identity in 40 aa overlap); etc. Contains PS00626 Regulator of chromosome condensation (RCC1) signature 2. | 0.680 |
lpqR | lpqI | Rv0838 | Rv0237 | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Probable conserved lipoprotein LpqI; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptidoglycan fragments. Acts as a regulator for GlcNAc-MurNAc levels by cleaving disaccharides and allowing the breakdown of MurNAc. | 0.454 |
lpqR | lprE | Rv0838 | Rv1252c | Probable conserved lipoprotein LpqR; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Probable lipoprotein LprE; Rv1252c, (MTCY50.30), len: 202 aa. Probable lipoprotein lprE, some similarity to Mycobacterium tuberculosis protein Rv3483c|MTCY13E12.36C (220 aa), FASTA scores: E(): 7e-05, (29.5% identity in 200 aa overlap). Contains possible N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachment site (PS00013). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | 0.401 |