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Rv1044 Rv1044 Rv1045 Rv1045 Rv2826c Rv2826c Rv0836c Rv0836c Rv2827c Rv2827c Rv0837c Rv0837c Rv0078B Rv0078B Rv0060 Rv0060 Rv0078A Rv0078A Rv0059 Rv0059 mbcT mbcT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rv1044Rv1044, (MTCY10G2.05c), len: 207 aa. Conserved hypothetical protein, similar to Mycobacterium tuberculosis hypothetical protein MTCY06G11.02C|P96837 (289 aa), fasta scores: E(): 8.9e-06, (30.7% identity in 150 aa overlap). Some similarity to U36837|LLU36837_1 Lactococcus lactis plasmid pNP40 (287 aa), FASTA scores: opt: 147, E (): 0.0087, (29.7% identity in 91 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). (207 aa)    
Predicted Functional Partners:
Rv1045
Hypothetical protein; Rv1045, (MTCY10G2.04c), len: 293 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007).
 
  
 0.999
Rv2826c
Hypothetical protein; Rv2826c, (MTCY16B7.16), len: 294 aa. Hypothetical unknown protein.
  
  
 0.883
Rv0836c
Hypothetical protein; Rv0836c, (MTV043.29c), len: 217 aa (start uncertain). Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007).
 
  
 0.880
Rv2827c
Hypothetical protein; Rv2827c, (MTCY16B7.15), len: 295 aa. Hypothetical unknown protein, equivalent to AAK47219 from Mycobacterium tuberculosis strain CDC1551 (315 aa) but shorter 20 aa.
   
  
 0.870
Rv0837c
Hypothetical protein; Rv0837c, (MTV043.30c), len: 342 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007).
 
  
 0.831
Rv0078B
Rv0078B, len: 68 aa. Conserved protein.
      
 0.815
Rv0060
Rv0060, (MTV030.03), len: 352 aa. Conserved hypothetical protein.
      
 0.803
Rv0078A
Rv0078A, len: 197 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007).
      
 0.803
Rv0059
Hypothetical protein; Rv0059, (MTV030.02), len: 230 aa. Hypothetical unknown protein.
      
 0.656
mbcT
Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Neutralized by cognate antitoxin MbcA. Degrades NAD(+) by phosphorolysis. Expression in the absence of its cognate antitoxin MbcA causes dramatic reduction of intracellular NAD(+) levels and is deleterious to cell growth, causing cell death. In a SCID mouse infection model, mice infected with bacteria overexpressing this protein survive longer. Overexpression of this protein in a mouse infection model at 21 days leads to bacterial death, and shows a synergistic 100-fold increase in mouse survival when combi [...]
   
  
 0.653
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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