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Rv1060 Rv1060 Rv1061 Rv1061 Rv1062 Rv1062 Rv1059 Rv1059 fadD14 fadD14 PE_PGRS42 PE_PGRS42 Rv3899c Rv3899c PE_PGRS36 PE_PGRS36 Rv1057 Rv1057 Rv3768 Rv3768 Rv0048c Rv0048c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rv1060Unknown protein; Rv1060, (MTV017.13), len: 157 aa. Unknown protein. (157 aa)    
Predicted Functional Partners:
Rv1061
Conserved protein; Rv1061, (MTV017.14), len: 287 aa. Conserved protein,similar to hypothetical proteins from various bacteria e.g. D64002|SYCSLRD_75 Synechocystis sp. PCC6803 (304 aa),FASTA scores: opt: 245, E():1.2e-09, (27.1% identity in 258 aa overlap).
 
    0.853
Rv1062
Rv1062, (MTV017.15), len: 285 aa. Conserved hypothetical protein, some similarity to AL079356|SC6G9_10 hypothetical protein in Streptomyces coelicolor (289 aa),FASTA scores: opt: 556, E(): 1.2e-27, (39.0% identity in 287 aa overlap), and Z99111|BSUB0008_176 Bacillus subtilis (260aa), FASTA scores: opt: 163, E(): 0.0013, (27.4% identity in 179aa overlap).
       0.831
Rv1059
Conserved protein; Rv1059, (MTV017.12), len: 354 aa. Conserved protein,similar to Rv0926c|MTCY21C12.20c hypothetical protein from Mycobacterium tuberculosis (358 aa), FASTA scores: opt: 338, E(): 1.4e-14, (33.1% identity in 363 aa overlap).
  
    0.809
fadD14
Fatty-acid-CoA ligase FadD14; Rv1058, (MTV017.11), len: 543 aa. Probable fadD14,medium-chain fatty-acid-CoA synthetase, highly similar to many e.g. CAC32346.1|AL583945 putative fatty acid CoA ligase from Streptomyces coelicolor (558 aa); N-terminus of NP_419738.1|NC_002696 medium-chain-fatty-acid--CoA ligase from Caulobacter crescentus (1006 aa); Q00594|ALKK_PSEOL medium-chain-fatty-acid--CoA ligase from Pseudomonas oleovorans (546 aa), FASTA scores: opt: 1468, E(): 0,(41.1% identity in 538 aa overlap); etc. Contains PS00455 Putative AMP-binding domain signature. Belongs to the ATP-dep [...]
 
     0.775
PE_PGRS42
PE-PGRS family protein PE_PGRS42; Rv2487c, (MTV008.43c), len: 694 aa. PE_PGRS42,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of Gly-rich proteins (see citation below),similar to many e.g. AAK47245|MT2919 PE_PGRS family protein from Mycobacterium tuberculosis strain CDC1515 (663 aa),FASTA scores: opt: 2317, E(): 2.3e-84, (58.35% identity in 622 aa overlap); etc.
  
     0.718
Rv3899c
Rv3899c, (MTCY15F10.13), len: 410 aa. Conserved hypothetical protein, similar in part to proteins from Mycobacterium tuberculosis strains H37Rv and CDC1551. Region between aa 29-80 is strictly identical to P96909 hypothetical 15.1 KDA protein (fragment) (143 aa) FASTA scores: opt: 562, E(): 4e-16, (69.0% identity in 142 aa overlap); and the N-terminal end is highly similar, but longer 65 aa, to O07266 hypothetical 13.7 KDA protein (fragment) (143 aa), FASTA scores: opt: 562, E(): 4e-16,(69.0% identity in 142 aa overlap). Highly similar to C-terminal end of Q10690|YK82_MYCTU|Rv2082|MTCY [...]
  
     0.686
PE_PGRS36
PE-PGRS family protein PE_PGRS36; Rv2098c, (MTCY49.38c), len: 434 aa. PE_PGRS36,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below). Frameshifted near N-terminus (see Rv2099c|PE21).
  
    0.685
Rv1057
Rv1057, (MTV017.10), len: 393 aa. Conserved hypothetical protein, some similarity to X84710|MMSAG_1 surface antigen of Methanosarcina mazeii (491 aa), FASTA scores: opt: 363, E():6.2e-15, (31.3% identity in 294 aa overlap). Regulated by MprA (Rv0981) under physiological conditions and environmental stress (SDS and Triton X-100) (See He et al., 2006).
 
     0.575
Rv3768
Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein.
  
     0.560
Rv0048c
Possible membrane protein; Rv0048c, MTCY21D4.11c, len: 289 aa. Possible membrane protein.
  
    0.548
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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