Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
There are several matches for 'Rv1196'.
Please select one from the list below and press Continue to proceed.
<- Back
Continue ->
organism
protein
1)
Mycobacterium tuberculosis H37Rv
PPE18 - PPE family protein PPE18; Could be a crucial virulence factor for intracellular survival of M.tuberculosis. Favors development of Th2-type response, and downregulates the proinflammatory and Th1-type response. Specifically interacts with the human Toll-like receptor 2 (TLR2), leading to an early and sustained activation of p38 MAPK, which induces IL-10 production and activates Th2-type immune response. Also inhibits proinflammatory cytokines IL-12p40 and TNF-alpha production. Acts by upregulating the expression as well as tyrosine phosphorylation of suppressor of cytokine signaling 3 ( [...]
[a.k.a.
Rv1196
, CCP43952.1, NZ_NVQJ01000025.1]
2)
Mycobacterium tuberculosis H37Rv
PPE19 - Rv1361c, (MTCY02B10.25c), len: 396 aa. PPE19 (alternate gene name: mtb39b). Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, highly similar to many e.g.
Rv1196
|MTCI364.08|PPE18, FASTA scores: E(): 0, (84.9% identity in 397 aa overlap); MTCY274.23c (42.3% identity in 416 aa overlap); etc. Contains PS00501 Signal peptidases I serine active site. Note that expression of Rv1361c was demonstrated in lysates by immunodetection (see Dillon et al., 1999). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004).
[a.k.a. Rv1361c, CCP44119.1, PPE family protein PPE19]
3)
Mycobacterium tuberculosis H37Rv
PPE69 - Rv3892c, (MTCY15F10.20), len: 399 aa. PPE69, Member of the Mycobacterium tuberculosis PPE family of conserved proteins, similar to many e.g. O05298|
Rv1196
|MTCI364.08 from Mycobacterium leprae (391 aa), FASTA scores: opt: 348,E(): 2.2e-08, (26.6% identity in 380 aa overlap).
[a.k.a. CCP46721.1, Rv3892c, mtv:RVBD_3892c]