node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0048c | Rv0875c | Rv0048c | Rv0875c | Possible membrane protein; Rv0048c, MTCY21D4.11c, len: 289 aa. Possible membrane protein. | Rv0875c, (MTCY31.03c), len: 162 aa. Possible conserved exported protein, equivalent to MLCB57_11|O33056 possible exported protein from Mycobacterium leprae (162 aa), FASTA scores: opt: 789, E(): 0, (71.4% identity in 161 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). Predicted to be an outer membrane protein (See Song et al.,2008). | 0.756 |
Rv0048c | Rv1353c | Rv0048c | Rv1353c | Possible membrane protein; Rv0048c, MTCY21D4.11c, len: 289 aa. Possible membrane protein. | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | 0.680 |
Rv0048c | Rv3779 | Rv0048c | Rv3779 | Possible membrane protein; Rv0048c, MTCY21D4.11c, len: 289 aa. Possible membrane protein. | Probable conserved transmembrane protein alanine and leucine rich; Rv3779, (MTCY13D12.13), len: 666 aa. Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane ala-, leu-rich protein, equivalent to Q9CD98|ML0116 putative membrane protein from Mycobacterium leprae (654 aa), FASTA scores: opt: 1991, E(): 2e-112, (66.5% identity in 666 aa overlap). Shows some similarity with Q9RRU0|DR2395 putative NA+/H+ antiporter from Deinococcus radiodurans (458 aa), FASTA scores: opt: 138, E(): 0.69,(31.9% identity in 138 aa overl [...] | 0.773 |
Rv0081 | Rv1353c | Rv0081 | Rv1353c | Rv0081, (MTV030.25), len: 114 aa. Probable transcriptional regulator, highly similar to others. | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | 0.695 |
Rv0875c | Rv0048c | Rv0875c | Rv0048c | Rv0875c, (MTCY31.03c), len: 162 aa. Possible conserved exported protein, equivalent to MLCB57_11|O33056 possible exported protein from Mycobacterium leprae (162 aa), FASTA scores: opt: 789, E(): 0, (71.4% identity in 161 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). Predicted to be an outer membrane protein (See Song et al.,2008). | Possible membrane protein; Rv0048c, MTCY21D4.11c, len: 289 aa. Possible membrane protein. | 0.756 |
Rv0875c | Rv1353c | Rv0875c | Rv1353c | Rv0875c, (MTCY31.03c), len: 162 aa. Possible conserved exported protein, equivalent to MLCB57_11|O33056 possible exported protein from Mycobacterium leprae (162 aa), FASTA scores: opt: 789, E(): 0, (71.4% identity in 161 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). Predicted to be an outer membrane protein (See Song et al.,2008). | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | 0.730 |
Rv0875c | Rv3779 | Rv0875c | Rv3779 | Rv0875c, (MTCY31.03c), len: 162 aa. Possible conserved exported protein, equivalent to MLCB57_11|O33056 possible exported protein from Mycobacterium leprae (162 aa), FASTA scores: opt: 789, E(): 0, (71.4% identity in 161 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). Predicted to be an outer membrane protein (See Song et al.,2008). | Probable conserved transmembrane protein alanine and leucine rich; Rv3779, (MTCY13D12.13), len: 666 aa. Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane ala-, leu-rich protein, equivalent to Q9CD98|ML0116 putative membrane protein from Mycobacterium leprae (654 aa), FASTA scores: opt: 1991, E(): 2e-112, (66.5% identity in 666 aa overlap). Shows some similarity with Q9RRU0|DR2395 putative NA+/H+ antiporter from Deinococcus radiodurans (458 aa), FASTA scores: opt: 138, E(): 0.69,(31.9% identity in 138 aa overl [...] | 0.745 |
Rv0895 | Rv1353c | Rv0895 | Rv1353c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | 0.740 |
Rv0895 | Rv1354c | Rv0895 | Rv1354c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). | Conserved hypothetical protein; Rv1354c, (MTCY02B10.18c), len: 623 aa. Conserved hypothetical protein, similar to many hypothetical proteins e.g. the C-terminus of G1001455 Synechocystis sp. (1244 aa), FASTA scores: opt: 933, E(): 0, (36.8% identity in 462 aa overlap); also similar to Rv1357c|MTCY02B10.21c (34.0% identity in 253 aa overlap). | 0.809 |
Rv0895 | Rv1356c | Rv0895 | Rv1356c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). | Hypothetical protein; Rv1356c, (MTCY02B10.20c), len: 263 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.744 |
Rv0895 | Rv1358 | Rv0895 | Rv1358 | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). | Rv1358, (MTCY02B10.22), len: 1159 aa. Probable transcriptional regulatory protein, some similarity to AFSR_STRCO|P25941 regulatory protein afsr from Streptomyces coelicolor (993 aa), FASTA scores: opt: 210, E(): 5.5e-06,(27.5% identity in 739 aa overlap). Similar also to Rv0890C|MTCY31.18c (65.5% identity in 884 aa overlap) and to Rv1359|MTCY02B10.23 (43.7% identity in 197 aa overlap). Contains PS00017 ATP/GTP-binding site motif A, PS00622 Bacterial regulatory proteins, luxR family signature. Helix turn helix motif present at aa 1116-1137, (Score 1291,+3.59 SD). | 0.806 |
Rv0895 | moeY | Rv0895 | Rv1355c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). | Rv1355c, (MTCY02B10.19c), len: 715 aa. Possible moeY, Molybdopterin biosynthesis protein, very weak similarity to MOEB_ECOLI|P12282 molybdopterin biosynthesis moeb protein (249 aa), FASTA scores, opt: 180, E(): 8.5e-05, (29.3% identity in 174 aa overlap). | 0.821 |
Rv1353c | Rv0048c | Rv1353c | Rv0048c | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Possible membrane protein; Rv0048c, MTCY21D4.11c, len: 289 aa. Possible membrane protein. | 0.680 |
Rv1353c | Rv0081 | Rv1353c | Rv0081 | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Rv0081, (MTV030.25), len: 114 aa. Probable transcriptional regulator, highly similar to others. | 0.695 |
Rv1353c | Rv0875c | Rv1353c | Rv0875c | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Rv0875c, (MTCY31.03c), len: 162 aa. Possible conserved exported protein, equivalent to MLCB57_11|O33056 possible exported protein from Mycobacterium leprae (162 aa), FASTA scores: opt: 789, E(): 0, (71.4% identity in 161 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). Predicted to be an outer membrane protein (See Song et al.,2008). | 0.730 |
Rv1353c | Rv0895 | Rv1353c | Rv0895 | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). | 0.740 |
Rv1353c | Rv1354c | Rv1353c | Rv1354c | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Conserved hypothetical protein; Rv1354c, (MTCY02B10.18c), len: 623 aa. Conserved hypothetical protein, similar to many hypothetical proteins e.g. the C-terminus of G1001455 Synechocystis sp. (1244 aa), FASTA scores: opt: 933, E(): 0, (36.8% identity in 462 aa overlap); also similar to Rv1357c|MTCY02B10.21c (34.0% identity in 253 aa overlap). | 0.981 |
Rv1353c | Rv1356c | Rv1353c | Rv1356c | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Hypothetical protein; Rv1356c, (MTCY02B10.20c), len: 263 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.972 |
Rv1353c | Rv1358 | Rv1353c | Rv1358 | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Rv1358, (MTCY02B10.22), len: 1159 aa. Probable transcriptional regulatory protein, some similarity to AFSR_STRCO|P25941 regulatory protein afsr from Streptomyces coelicolor (993 aa), FASTA scores: opt: 210, E(): 5.5e-06,(27.5% identity in 739 aa overlap). Similar also to Rv0890C|MTCY31.18c (65.5% identity in 884 aa overlap) and to Rv1359|MTCY02B10.23 (43.7% identity in 197 aa overlap). Contains PS00017 ATP/GTP-binding site motif A, PS00622 Bacterial regulatory proteins, luxR family signature. Helix turn helix motif present at aa 1116-1137, (Score 1291,+3.59 SD). | 0.785 |
Rv1353c | Rv2250c | Rv1353c | Rv2250c | Probable transcriptional regulatory protein; Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region. | Rv2250c, (MTCY427.32c), len: 189 aa. Possible transcriptional regulatory protein, TetR family. Start unclear; ORF has been shortened since first submission to avoid overlap with Rv2251 (-30 aa). Contains probable helix-turn-helix motif (Score 2243, +6.70 SD). | 0.742 |