node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1739c | Rv1742 | Rv1739c | Rv1742 | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | 0.575 |
Rv1739c | pknE | Rv1739c | Rv1743 | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.419 |
Rv1739c | vapB34 | Rv1739c | Rv1740 | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | 0.566 |
Rv1739c | vapC34 | Rv1739c | Rv1741 | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | Possible toxin VapC34. Contains PIN domain; Toxic component of a possible type II toxin-antitoxin (TA) system. A putative RNase. Its cognate antitoxin is VapB34 (By similarity).; Belongs to the PINc/VapC protein family. | 0.572 |
Rv1742 | Rv1739c | Rv1742 | Rv1739c | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | 0.575 |
Rv1742 | pknE | Rv1742 | Rv1743 | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.540 |
Rv1742 | vapB34 | Rv1742 | Rv1740 | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | 0.786 |
Rv1742 | vapC34 | Rv1742 | Rv1741 | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | Possible toxin VapC34. Contains PIN domain; Toxic component of a possible type II toxin-antitoxin (TA) system. A putative RNase. Its cognate antitoxin is VapB34 (By similarity).; Belongs to the PINc/VapC protein family. | 0.792 |
pknE | Rv1739c | Rv1743 | Rv1739c | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | 0.419 |
pknE | Rv1742 | Rv1743 | Rv1742 | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | 0.540 |
pknE | vapB34 | Rv1743 | Rv1740 | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | 0.540 |
pknE | vapC34 | Rv1743 | Rv1741 | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Possible toxin VapC34. Contains PIN domain; Toxic component of a possible type II toxin-antitoxin (TA) system. A putative RNase. Its cognate antitoxin is VapB34 (By similarity).; Belongs to the PINc/VapC protein family. | 0.536 |
vapB28 | vapB30 | Rv0608 | Rv0623 | Possible antitoxin VapB28; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC28. | Possible antitoxin VapB30; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC30. | 0.687 |
vapB28 | vapB34 | Rv0608 | Rv1740 | Possible antitoxin VapB28; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC28. | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | 0.619 |
vapB28 | vapC34 | Rv0608 | Rv1741 | Possible antitoxin VapB28; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC28. | Possible toxin VapC34. Contains PIN domain; Toxic component of a possible type II toxin-antitoxin (TA) system. A putative RNase. Its cognate antitoxin is VapB34 (By similarity).; Belongs to the PINc/VapC protein family. | 0.455 |
vapB30 | vapB28 | Rv0623 | Rv0608 | Possible antitoxin VapB30; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC30. | Possible antitoxin VapB28; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC28. | 0.687 |
vapB30 | vapC34 | Rv0623 | Rv1741 | Possible antitoxin VapB30; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC30. | Possible toxin VapC34. Contains PIN domain; Toxic component of a possible type II toxin-antitoxin (TA) system. A putative RNase. Its cognate antitoxin is VapB34 (By similarity).; Belongs to the PINc/VapC protein family. | 0.876 |
vapB34 | Rv1739c | Rv1740 | Rv1739c | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | Probable sulphate-transport transmembrane protein ABC transporter; Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein. | 0.566 |
vapB34 | Rv1742 | Rv1740 | Rv1742 | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | Unknown protein; Rv1742, (MTCY28.04,MTCY04C12.27), len: 245 aa. Unknown protein. | 0.786 |
vapB34 | pknE | Rv1740 | Rv1743 | Possible antitoxin VapB34; Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC34. | Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E); Important for survival of the bacterium in the host during infection. Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress. May contribute to the adaptation of M.tuberculosis during stress conditions by maintaining the cellular integrity. Can phosphorylate the FHA domain of Rv1747. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.540 |