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vapC13 vapC13 vapB13 vapB13 vapC44 vapC44 vapC38 vapC38 vapC27 vapC27 vapB43 vapB43 vapC39 vapC39 PE_PGRS34 PE_PGRS34 vapB49 vapB49 vapC41 vapC41 Rv2209 Rv2209
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
vapC13Possible toxin VapC13; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB13 (By similarity). (131 aa)    
Predicted Functional Partners:
vapB13
Possible antitoxin VapB13; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC13.
  
    0.884
vapC44
Possible toxin VapC44. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB44 (By similarity).
  
  
 0.710
vapC38
Possible toxin VapC38. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB38 (By similarity).
  
  
 0.703
vapC27
Possible toxin VapC27. Contains PIN domain; Probably the toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB27. Belongs to the PINc/VapC protein family.
   
  
 0.660
vapB43
Possible antitoxin VapB43; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC43.
  
 
 0.650
vapC39
Possible toxin VapC39. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB39.
  
  
 0.622
PE_PGRS34
PE-PGRS family protein PE_PGRS34; Rv1840c, (MTCY359.33), len: 515 aa. PE_PGRS34,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below). Similar to many e.g. Y03A_MYCTU|Q10637 hypothetical glycine-rich 49.6 kDa protein (603 aa), FASTA scores: opt: 1693, E(): 0, (53.1% identity in 612 aa overlap); etc.
       0.621
vapB49
Conserved protein; Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC49 (Potential).
 
  
 0.616
vapC41
Possible toxin VapC41. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB41.
   
  
 0.610
Rv2209
Rv2209, (MTCY190.20), len: 512 aa. Probable conserved integral membrane protein, similar to but longer than Rv0246 gp|AL021929|MTV 034_12 Mycobacterium tuberculosis (436 aa). FASTA score: opt: 712, E(): 2.8e-32; 33.4% identity in 422 aa overlap.
  
    0.598
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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