STRINGSTRING
Rv1947 Rv1947 dinG dinG rpoB rpoB rpoA rpoA rpoZ rpoZ polA polA Rv2529 Rv2529 Rv2090 Rv2090 helZ helZ rpoC rpoC Rv3479 Rv3479
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rv1947Hypothetical protein; Rv1947, (MTCY09F9.17c), len: 133 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). (133 aa)    
Predicted Functional Partners:
dinG
Probable ATP-dependent helicase DinG; Probable helicase involved in DNA repair and perhaps also replication; Belongs to the helicase family. DinG subfamily.
   
 0.890
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.856
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.854
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 0.847
polA
Probable DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.787
Rv2529
Hypothetical protein; Rv2529, (MTCY159.27c), len: 463 aa. Hypothetical unknown protein. Note that C-terminal part is similar to short region of Q53609|MTS1_STRAL|SALIM modification methylase SALI from Streptomyces albus G (587 aa), FASTA scores: opt: 170, E(): 0.016, (59.45% identity in 37 aa overlap).
 
 0.786
Rv2090
Probable 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.
  
 0.766
helZ
Probable helicase HelZ; Rv2101, (MTV020.01), len: 1013 aa. Probable helZ,helicase, similar to many. Nucleotide position 2361623 in the genome sequence has been corrected, A:C resulting in M462L.
  
 0.712
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.688
Rv3479
Rv3479, (MTCY13E12.32), len: 1021 aa. Possible transmembrane protein, with hydrophobic stretches at C-terminus. Start changed since first submission (-54 aa). Alternative nucleotide at position 3896340 (T->G; L174R) has been observed.
  
    0.652
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.