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There are several matches for 'Rv2074'.
Please select one from the list below and press Continue to proceed.
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organism
protein
1)
Mycobacterium tuberculosis H37Rv
Rv2074
- F420H(2)-dependent biliverdin reductase; Catalyzes the F420H(2)-dependent reduction of biliverdin- IXalpha at C10 position, leading to bilirubin-IXalpha, a potent antioxidant. As biliverdin-IXalpha is produced in high amounts in macrophages infected with M.tuberculosis, its reduction by
Rv2074
may play a role in protecting mycobacteria against oxidative stress, aiding the persistence of M.tuberculosis infection.
2)
Mycobacterium tuberculosis H37Rv
Rv0121c - Conserved protein; Rv0121c, (MTCI418B.03c), len: 144 aa. Conserved protein, showing some similarity with others proteins from Mycobacterium tuberculosis e.g. Rv1155, Rv1875,
Rv2074
,etc.
[a.k.a. CCP42846.1, I6X8K2, O07171]
3)
Mycobacterium tuberculosis H37Rv
Rv1155 - F420H(2)-dependent reductase Rv1155; F420H(2)-dependent reductase able to catalyze the reduction of biliverdin-IXalpha to bilirubin-IXalpha in vitro. However, kinetic parameters show that it is less efficient than the biliverdin reductase
Rv2074
and suggest biliverdin-IXalpha is unlikely to be the native substrate of Rv1155, which probably catalyzes the reduction of an alternative molecule in vivo. Binds coenzyme F420, but does not bind FMN or other flavins. Cannot use pyridoxine 5'-phosphate, pyridoxamine 5'-phosphate, pyridoxal 5'- phosphate (PLP), the anti-tuberculosis drug PA-824 o [...]
[a.k.a. CCP43910.1, NZ_NVQJ01000025.1, Pyridoxamine 5'-phosphate oxidase]
4)
Mycobacterium tuberculosis H37Rv
Rv1875 - Conserved protein; Rv1875, (MTCY180.43c), len: 147 aa. Conserved protein. Some similarity to Mycobacterium tuberculosis hypothetical proteins e.g. Rv1155|MTCI65.22|Z95584 (147 aa), FASTA scores: opt: 178, E(): 7.4e-06, (26.9% identity in 130 aa overlap); Rv0121c and
Rv2074
. Also similar to AL079356|SC6G9.21 hypothetical protein from Streptomyces coelicolor (144 aa), FASTA scores: opt: 239, E(): 3.1 e-09,(38.7% identity in 137 aa overlap).
[a.k.a. CCP44641.1, WP_003899059.1, Conserved protein]