node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv2148c | ftsQ | Rv2148c | Rv2151c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Possible cell division protein FtsQ; Essential cell division protein. | 0.704 |
Rv2148c | ftsW | Rv2148c | Rv2154c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.651 |
Rv2148c | ftsZ | Rv2148c | Rv2150c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.901 |
Rv2148c | murC | Rv2148c | Rv2152c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Probable UDP-N-acetylmuramate-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.772 |
Rv2148c | murD | Rv2148c | Rv2155c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.621 |
Rv2148c | murG | Rv2148c | Rv2153c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II). | 0.724 |
Rv2148c | murX | Rv2148c | Rv2156c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan. | 0.653 |
Rv2148c | sepF | Rv2148c | Rv2147c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.969 |
Rv2148c | yfiH | Rv2148c | Rv2149c | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved protein YfiH; Multicopper oxidase with polyphenol oxidase activity. | 0.978 |
ftsQ | Rv2148c | Rv2151c | Rv2148c | Possible cell division protein FtsQ; Essential cell division protein. | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.704 |
ftsQ | ftsW | Rv2151c | Rv2154c | Possible cell division protein FtsQ; Essential cell division protein. | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.999 |
ftsQ | ftsZ | Rv2151c | Rv2150c | Possible cell division protein FtsQ; Essential cell division protein. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.991 |
ftsQ | murC | Rv2151c | Rv2152c | Possible cell division protein FtsQ; Essential cell division protein. | Probable UDP-N-acetylmuramate-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ftsQ | murD | Rv2151c | Rv2155c | Possible cell division protein FtsQ; Essential cell division protein. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.992 |
ftsQ | murG | Rv2151c | Rv2153c | Possible cell division protein FtsQ; Essential cell division protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II). | 0.998 |
ftsQ | murX | Rv2151c | Rv2156c | Possible cell division protein FtsQ; Essential cell division protein. | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan. | 0.937 |
ftsQ | pbpB | Rv2151c | Rv2163c | Possible cell division protein FtsQ; Essential cell division protein. | Probable penicillin-binding membrane protein PbpB; Synthesis of cross-linked peptidoglycan from the lipid intermediates; Belongs to the transpeptidase family. | 0.994 |
ftsQ | sepF | Rv2151c | Rv2147c | Possible cell division protein FtsQ; Essential cell division protein. | Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.980 |
ftsQ | yfiH | Rv2151c | Rv2149c | Possible cell division protein FtsQ; Essential cell division protein. | Conserved protein YfiH; Multicopper oxidase with polyphenol oxidase activity. | 0.740 |
ftsW | Rv2148c | Rv2154c | Rv2148c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Conserved protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.651 |