node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1024 | ftsQ | Rv1024 | Rv2151c | Rv1024, (MTCY10G2.25c), len: 228 aa. Possible conserved membrane protein, with a hydrophobic region from aa 83-101. Equivalent to ML0256|NP_301311.1|NC_002677 possible conserved membrane protein from Mycobacterium leprae (227 aa), S&W scores: 178, E()= 2e-72, Identities: 145/203 (71%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Possible cell division protein FtsQ; Essential cell division protein. | 0.983 |
Rv1024 | ftsW | Rv1024 | Rv2154c | Rv1024, (MTCY10G2.25c), len: 228 aa. Possible conserved membrane protein, with a hydrophobic region from aa 83-101. Equivalent to ML0256|NP_301311.1|NC_002677 possible conserved membrane protein from Mycobacterium leprae (227 aa), S&W scores: 178, E()= 2e-72, Identities: 145/203 (71%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.741 |
Rv1024 | pbpB | Rv1024 | Rv2163c | Rv1024, (MTCY10G2.25c), len: 228 aa. Possible conserved membrane protein, with a hydrophobic region from aa 83-101. Equivalent to ML0256|NP_301311.1|NC_002677 possible conserved membrane protein from Mycobacterium leprae (227 aa), S&W scores: 178, E()= 2e-72, Identities: 145/203 (71%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable penicillin-binding membrane protein PbpB; Synthesis of cross-linked peptidoglycan from the lipid intermediates; Belongs to the transpeptidase family. | 0.736 |
Rv1024 | rodA | Rv1024 | Rv0017c | Rv1024, (MTCY10G2.25c), len: 228 aa. Possible conserved membrane protein, with a hydrophobic region from aa 83-101. Equivalent to ML0256|NP_301311.1|NC_002677 possible conserved membrane protein from Mycobacterium leprae (227 aa), S&W scores: 178, E()= 2e-72, Identities: 145/203 (71%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable cell division protein RodA; Rv0017c, (MTCY10H4.17c), len: 469 aa. Probable rodA (alternate gene name: ftsW), cell division protein,integral membrane protein. Belongs to the FTSW/RODA/SPOVE family. | 0.673 |
ftsQ | Rv1024 | Rv2151c | Rv1024 | Possible cell division protein FtsQ; Essential cell division protein. | Rv1024, (MTCY10G2.25c), len: 228 aa. Possible conserved membrane protein, with a hydrophobic region from aa 83-101. Equivalent to ML0256|NP_301311.1|NC_002677 possible conserved membrane protein from Mycobacterium leprae (227 aa), S&W scores: 178, E()= 2e-72, Identities: 145/203 (71%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | 0.983 |
ftsQ | ftsW | Rv2151c | Rv2154c | Possible cell division protein FtsQ; Essential cell division protein. | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.999 |
ftsQ | ftsZ | Rv2151c | Rv2150c | Possible cell division protein FtsQ; Essential cell division protein. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.991 |
ftsQ | murC | Rv2151c | Rv2152c | Possible cell division protein FtsQ; Essential cell division protein. | Probable UDP-N-acetylmuramate-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ftsQ | murD | Rv2151c | Rv2155c | Possible cell division protein FtsQ; Essential cell division protein. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.992 |
ftsQ | murF | Rv2151c | Rv2157c | Possible cell division protein FtsQ; Essential cell division protein. | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.984 |
ftsQ | murG | Rv2151c | Rv2153c | Possible cell division protein FtsQ; Essential cell division protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II). | 0.998 |
ftsQ | pbpB | Rv2151c | Rv2163c | Possible cell division protein FtsQ; Essential cell division protein. | Probable penicillin-binding membrane protein PbpB; Synthesis of cross-linked peptidoglycan from the lipid intermediates; Belongs to the transpeptidase family. | 0.994 |
ftsQ | rodA | Rv2151c | Rv0017c | Possible cell division protein FtsQ; Essential cell division protein. | Probable cell division protein RodA; Rv0017c, (MTCY10H4.17c), len: 469 aa. Probable rodA (alternate gene name: ftsW), cell division protein,integral membrane protein. Belongs to the FTSW/RODA/SPOVE family. | 0.970 |
ftsQ | sepF | Rv2151c | Rv2147c | Possible cell division protein FtsQ; Essential cell division protein. | Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.980 |
ftsW | Rv1024 | Rv2154c | Rv1024 | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Rv1024, (MTCY10G2.25c), len: 228 aa. Possible conserved membrane protein, with a hydrophobic region from aa 83-101. Equivalent to ML0256|NP_301311.1|NC_002677 possible conserved membrane protein from Mycobacterium leprae (227 aa), S&W scores: 178, E()= 2e-72, Identities: 145/203 (71%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | 0.741 |
ftsW | ftsQ | Rv2154c | Rv2151c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Possible cell division protein FtsQ; Essential cell division protein. | 0.999 |
ftsW | ftsZ | Rv2154c | Rv2150c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.997 |
ftsW | murC | Rv2154c | Rv2152c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Probable UDP-N-acetylmuramate-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
ftsW | murD | Rv2154c | Rv2155c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.992 |
ftsW | murF | Rv2154c | Rv2157c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.994 |