STRINGSTRING
stp stp Rv1776c Rv1776c Rv1410c Rv1410c ephF ephF
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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stpIntegral membrane drug efflux protein Stp; Contributes to spectinomycin and tetracycline resistance. Belongs to the major facilitator superfamily. EmrB family. (537 aa)    
Predicted Functional Partners:
Rv1776c
Rv1776c, (MTCY25C11.03c), len: 186 aa. Possible regulatory protein, some similarity to Mycobacterium tuberculosis Rv1255c|Q11063 hypothetical transcriptional regulator (202 aa), FASTA scores: opt: 270, E(): 9.7e-09,(28.3% identity in 191 aa overlap). Contains possible helix-turn-helix motif at aa 37-58 (+3.49 SD).
  
  
 0.469
Rv1410c
Aminoglycosides/tetracycline-transport integral membrane protein; In association with lipoprotein LprG probably transports triacylglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation. Confers resistance to ethidium bromide, possibly acting as an efflux pump, requires LprG lipoprotein for normal function. With LprG maintains cell wall permeability. Probably required with LprG for normal surface localization of LAM. Overexpression of LprG and Rv1410c leads to increased levels of TAG in the culture medium. Belong [...]
  
  
0.446
ephF
Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase); Rv0134, (MTCI5.08), len: 300 aa. Possible ephE,epoxide hydrolase (see citation below), similar to others e.g. Q39856 epoxide hydrolase (341 aa), FASTA scores: opt: 369, E(): 4.6e-17, (27.2% identity in 335 aa overlap); etc. Also similar to MTCY09F9.26c from Mycobacterium tuberculosis (29.5% identity in 346 aa overlap).
     
 0.425
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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