Rv2365c, (MTCY27.15), len: 113 aa. Conserved hypothetical protein, highly similar to Q49767|ML0630|B1937_F3_101|CAC30138 Hypothetical protein from Mycobacterium leprae (108 aa), FASTA scores: opt: 426,E(): 1.4e-18, (67.9% identity in 106 aa overlap). Also highly similar to Q9RDF3|SCC77.05 from Streptomyces coelicolor (132 aa), FASTA scores: opt: 254, E(): 1.9e-18,(53.1% identity in 96 aa overlap). Equivalent to AAK46728 from Mycobacterium tuberculosis strain CDC1551 (93 aa) but longer 20 aa.

Rv2366c, (MTCY27.14), len: 435 aa. Probable conserved transmembrane protein, highly similar to Q9L2L3|SCC117.07 putative membrane protein from Streptomyces coelicolor (358 aa), FASTA scores: opt: 1159,E(): 5.5e-64, (53.0% identity in 353 aa overlap); ans similar to hypothetical proteins and hemolysin-related proteins e.g. Q9HN02|HLP|VNG2308G hemolysin protein from Halobacterium sp. strain NRC-1 (457 aa), FASTA scores: opt: 623, E(): 6.2e-31, (28.4% identity in 433 aa overlap); etc. Potential transmembrane protein with 2 CBS domains. Belongs to the UPF0053 family.

Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

Rv2368c, (MTCY27.12), len: 352 aa. Probable phoH1,phoH-like protein (phosphate starvation-induced protein),probably ATP-binding protein, equivalent to Q49751|PHOL_MYCLE| ML0627|B1937_F1_20 PHOH-like protein from Mycobacterium leprae (349 aa), FASTA scores: opt: 1952, E(): 4.7e-107, (88.9% identity in 352 aa overlap). Also highly similar to Q9L2L5|SCC117.05 PHOH-like protein from Streptomyces coelicolor (359 aa), FASTA scores: opt: 1407, E(): 3.6e-75, (63.6% identity in 349 aa overlap); Q9RSY1|DR1988 PHOH-related protein from Deinococcus radiodurans (380 aa), FASTA scores: opt: 1053, E( [...]

Probable GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.

Rv2371, (MTCY27.09c), len: 61 aa. PE_PGRS40, Short protein, member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to N-terminal part of others e.g. AAK44356|MT0132 PE_PGRS family protein from Mycobacterium tuberculosis strain CDC1551 (561 aa), FASTA scores: opt: 217, E(): 4.9e-08, (69.65% identity in 56 aa overlap); etc.