node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0012 | Rv1824 | Rv0012 | Rv1824 | Rv0012, (MTCY10H4.12), len: 262 aa. Probable conserved membrane protein. Belongs to superfamily DUF881. Contains probable N-terminal signal sequence. | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | 0.840 |
Rv0012 | Rv2375 | Rv0012 | Rv2375 | Rv0012, (MTCY10H4.12), len: 262 aa. Probable conserved membrane protein. Belongs to superfamily DUF881. Contains probable N-terminal signal sequence. | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | 0.423 |
Rv0012 | disA | Rv0012 | Rv3586 | Rv0012, (MTCY10H4.12), len: 262 aa. Probable conserved membrane protein. Belongs to superfamily DUF881. Contains probable N-terminal signal sequence. | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | 0.405 |
Rv0430 | Rv2375 | Rv0430 | Rv2375 | Rv0430, (MTCY22G10.27), len: 102 aa. Conserved hypothetical protein, equivalent to AC30882.1|AL583923 conserved hypothetical protein from Mycobacterium leprae (102 aa). Also highly similar to CAB93047.1|SCD95A.20|AL357432 hypothetical protein from Streptomyces coelicolor (84 aa). | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | 0.411 |
Rv0430 | Rv2466c | Rv0430 | Rv2466c | Rv0430, (MTCY22G10.27), len: 102 aa. Conserved hypothetical protein, equivalent to AC30882.1|AL583923 conserved hypothetical protein from Mycobacterium leprae (102 aa). Also highly similar to CAB93047.1|SCD95A.20|AL357432 hypothetical protein from Streptomyces coelicolor (84 aa). | Conserved protein; In vitro, the reduced form of Rv2466c catalyzes the reduction and activation of TP053, which is a thienopyrimidine derivative drug that can kill both replicating and non-replicating M.tuberculosis. | 0.432 |
Rv1823 | Rv1824 | Rv1823 | Rv1824 | Conserved protein; Rv1823, (MTCY01A11.20), len: 307 aa. Conserved protein, similar to P71582|MTCY10H4.12|RV0012 hypothetical protein CY10H4.12 from Mycobacterium tuberculosis (262 aa),FASTA scores: opt: 304, E(): 1.5e-12, (30.1% identity in 246 aa overlap). | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | 0.992 |
Rv1823 | Rv2375 | Rv1823 | Rv2375 | Conserved protein; Rv1823, (MTCY01A11.20), len: 307 aa. Conserved protein, similar to P71582|MTCY10H4.12|RV0012 hypothetical protein CY10H4.12 from Mycobacterium tuberculosis (262 aa),FASTA scores: opt: 304, E(): 1.5e-12, (30.1% identity in 246 aa overlap). | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | 0.448 |
Rv1824 | Rv0012 | Rv1824 | Rv0012 | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | Rv0012, (MTCY10H4.12), len: 262 aa. Probable conserved membrane protein. Belongs to superfamily DUF881. Contains probable N-terminal signal sequence. | 0.840 |
Rv1824 | Rv1823 | Rv1824 | Rv1823 | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | Conserved protein; Rv1823, (MTCY01A11.20), len: 307 aa. Conserved protein, similar to P71582|MTCY10H4.12|RV0012 hypothetical protein CY10H4.12 from Mycobacterium tuberculosis (262 aa),FASTA scores: opt: 304, E(): 1.5e-12, (30.1% identity in 246 aa overlap). | 0.992 |
Rv1824 | Rv2375 | Rv1824 | Rv2375 | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | 0.436 |
Rv1824 | disA | Rv1824 | Rv3586 | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | 0.419 |
Rv1929c | Rv2375 | Rv1929c | Rv2375 | Rv1929c, MTCY09F9.35, len: 214 aa. Conserved hypothetical protein, similar to SC4G6.14|AL096884 hypothetical protein from Streptomyces coelicolor (211 aa),FASTA scores: opt: 416, E(): 2.4e-22, (39.8% identity in 206 aa overlap). | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | 0.499 |
Rv2375 | Rv0012 | Rv2375 | Rv0012 | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Rv0012, (MTCY10H4.12), len: 262 aa. Probable conserved membrane protein. Belongs to superfamily DUF881. Contains probable N-terminal signal sequence. | 0.423 |
Rv2375 | Rv0430 | Rv2375 | Rv0430 | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Rv0430, (MTCY22G10.27), len: 102 aa. Conserved hypothetical protein, equivalent to AC30882.1|AL583923 conserved hypothetical protein from Mycobacterium leprae (102 aa). Also highly similar to CAB93047.1|SCD95A.20|AL357432 hypothetical protein from Streptomyces coelicolor (84 aa). | 0.411 |
Rv2375 | Rv1823 | Rv2375 | Rv1823 | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Conserved protein; Rv1823, (MTCY01A11.20), len: 307 aa. Conserved protein, similar to P71582|MTCY10H4.12|RV0012 hypothetical protein CY10H4.12 from Mycobacterium tuberculosis (262 aa),FASTA scores: opt: 304, E(): 1.5e-12, (30.1% identity in 246 aa overlap). | 0.448 |
Rv2375 | Rv1824 | Rv2375 | Rv1824 | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Rv1824, (MTCY1A11.19c), len: 121 aa. Conserved hypothetical membrane protein similar to P28265|SBP_BACSU sbp protein from Bacillus subtilis (121 aa), FASTA scores: opt: 261, E(): 1.9e-12, (38.9% identity in 113 aa overlap). | 0.436 |
Rv2375 | Rv1929c | Rv2375 | Rv1929c | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Rv1929c, MTCY09F9.35, len: 214 aa. Conserved hypothetical protein, similar to SC4G6.14|AL096884 hypothetical protein from Streptomyces coelicolor (211 aa),FASTA scores: opt: 416, E(): 2.4e-22, (39.8% identity in 206 aa overlap). | 0.499 |
Rv2375 | Rv2466c | Rv2375 | Rv2466c | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Conserved protein; In vitro, the reduced form of Rv2466c catalyzes the reduction and activation of TP053, which is a thienopyrimidine derivative drug that can kill both replicating and non-replicating M.tuberculosis. | 0.459 |
Rv2375 | disA | Rv2375 | Rv3586 | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | 0.717 |
Rv2375 | dnaJ2 | Rv2375 | Rv2373c | Rv2375, (MTCY27.05c), len: 105 aa. Conserved hypothetical protein, highly similar to only CAC32314|2SCD60.09c conserved hypothetical protein from Streptomyces coelicolor (98 aa), FASTA scores: opt: 425,E(): 5.7e-24, (63.25% identity in 98 aa overlap). | Probable chaperone protein DnaJ2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...] | 0.663 |