STRINGSTRING
Rv2452c Rv2452c mobA mobA korB korB korA korA Rv2456c Rv2456c
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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Rv2452cHypothetical protein; Rv2452c, (MTV008.08c), len: 48 aa. Hypothetical unknown protein (see citation below). (48 aa)    
Predicted Functional Partners:
mobA
Probable molybdopterin-guanine dinucleotide biosynthesis protein A MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
  
    0.721
korB
Probable oxidoreductase (beta subunit); Component of KG oxidoreductase (KOR) that catalyzes the CoA- dependent oxidative decarboxylation of 2-oxoglutarate (alpha- ketoglutarate, KG) to succinyl-CoA. Methyl viologen can act as electron acceptor in vitro; the physiologic electron acceptor is unknown. Is involved in the alternative TCA pathway that functions concurrently with fatty acid beta-oxidation. Since a growing body of evidence indicates that lipids (for example cholesterol and fatty acids) are a predominant growth substrate for M.tuberculosis during infection, flux through KOR lik [...]
  
    0.718
korA
Probable oxidoreductase (alpha subunit); Component of KG oxidoreductase (KOR) that catalyzes the CoA- dependent oxidative decarboxylation of 2-oxoglutarate (alpha- ketoglutarate, KG) to succinyl-CoA. Methyl viologen can act as electron acceptor in vitro; the physiologic electron acceptor is unknown. Is involved in the alternative TCA pathway that functions concurrently with fatty acid beta-oxidation. Since a growing body of evidence indicates that lipids (for example cholesterol and fatty acids) are a predominant growth substrate for M.tuberculosis during infection, flux through KOR li [...]
  
    0.707
Rv2456c
Rv2456c, (MTV008.12c), len: 418 aa. Probable conserved integral membrane transport protein, involved in a efflux system, weakly similar to many e.g. Q9RUR0|YD22_DEIRA|DR1322 putative sugar efflux transporter from Deinococcus radiodurans (389 aa), FASTA scores: opt: 224, E(): 8.4e-06, (24.45% identity in 409 aa overlap); Q9UYY0|PAB0913 multidrug resistance protein from Pyrococcus abyssi (410 aa), FASTA scores: opt: 210, E(): 5.6e-05,(21.8% identity in 408 aa overlap); etc. Contains PS00216 Sugar transport proteins signature 1.
  
    0.402
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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