node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PE2 | PE_PGRS46 | Rv0152c | Rv2634c | Rv0152c, (MTCI5.26c), len: 525 aa. PE2, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to ORF downstream Z92770|MTCI5_25 (588 aa),FASTA scores: opt: 1492, E(): 0, (54.7% identity in 464 aa overlap); and to many other PE family type members. Predicted to be an outer membrane protein (See Song et al.,2008). | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.515 |
PE2 | PPE67 | Rv0152c | Rv3739c | Rv0152c, (MTCI5.26c), len: 525 aa. PE2, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to ORF downstream Z92770|MTCI5_25 (588 aa),FASTA scores: opt: 1492, E(): 0, (54.7% identity in 464 aa overlap); and to many other PE family type members. Predicted to be an outer membrane protein (See Song et al.,2008). | Rv3739c, (MTV025.087c), len: 77 aa. PPE67, Member of the Mycobacterium tuberculosis PE family, showing high homology with O53269|Rv3022c|MTV012.36c (82 aa) FASTA scores: opt: 398, E(): 1.2e-19, (74.0% identity in 77 aa overlap); and similar to the N-termini of other PPE proteins e.g. O53265|Rv3018c|MTV012.32c (434 aa) FASTA scores: opt: 398, E(): 4.8e-19, (74.0% identity in 77 aa overlap). ORF ends at the stop codon at position 97470,which is not present in similar ORFs: MTV012_32, or MTCY21B4_4. Sequence homology with MTV012_32, and MTCY21B4_4 continues in the downstream ORF MTV025.08 [...] | 0.454 |
PE_PGRS46 | PE2 | Rv2634c | Rv0152c | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | Rv0152c, (MTCI5.26c), len: 525 aa. PE2, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to ORF downstream Z92770|MTCI5_25 (588 aa),FASTA scores: opt: 1492, E(): 0, (54.7% identity in 464 aa overlap); and to many other PE family type members. Predicted to be an outer membrane protein (See Song et al.,2008). | 0.515 |
PE_PGRS46 | PPE29 | Rv2634c | Rv1801 | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | PPE family protein PPE29; Could be required for host endothelial-cell invasion and/or intracellular survival; Belongs to the mycobacterial PPE family. | 0.548 |
PE_PGRS46 | PPE67 | Rv2634c | Rv3739c | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | Rv3739c, (MTV025.087c), len: 77 aa. PPE67, Member of the Mycobacterium tuberculosis PE family, showing high homology with O53269|Rv3022c|MTV012.36c (82 aa) FASTA scores: opt: 398, E(): 1.2e-19, (74.0% identity in 77 aa overlap); and similar to the N-termini of other PPE proteins e.g. O53265|Rv3018c|MTV012.32c (434 aa) FASTA scores: opt: 398, E(): 4.8e-19, (74.0% identity in 77 aa overlap). ORF ends at the stop codon at position 97470,which is not present in similar ORFs: MTV012_32, or MTCY21B4_4. Sequence homology with MTV012_32, and MTCY21B4_4 continues in the downstream ORF MTV025.08 [...] | 0.543 |
PE_PGRS46 | Rv2633c | Rv2634c | Rv2633c | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | Hypothetical protein; Rv2633c, (MTCY441.03c), len: 161 aa. Hypothetical unknown protein. | 0.444 |
PE_PGRS46 | Rv2635 | Rv2634c | Rv2635 | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | Hypothetical protein; Rv2635, (MTCY441.05), len: 80 aa. Hypothetical unknown protein. | 0.575 |
PE_PGRS46 | Rv2636 | Rv2634c | Rv2636 | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | Rv2636, (MTCY441.06), len: 225 aa. Conserved hypothetical protein, showing some similarity with various proteins: Q98FG2|MLL3789 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (239 aa), FASTA scores: opt: 304, E(): 3.7e-13, (31.55% identity in 187 aa overlap); CAC46568|SMC04451 putative chloramphenicol phosphotransferase protein from Rhizobium meliloti (Sinorhizobium meliloti) (220 aa), FASTA scores: opt: 175,E(): 0.00014, (28.0% identity in 225 aa overlap); Q56148|CPT_STRVL chloramphenicol 3-O phosphotransferase from Streptomyces violaceus (Streptomyces venezuelae) (178 [...] | 0.568 |
PE_PGRS46 | zmp1 | Rv2634c | Rv0198c | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | Rv0198c, (MTV033.06c), len: 663 aa. Probable zmp1,zinc metalloprotease, equivalent to Z95398|MLCL622.12c from Mycobacterium leprae (667 aa), FASTA scores: opt: 3710,E(): 0, (80.8 % identity in 667 aa overlap). Also similar to many other metalloproteases e.g. members of the eukaryotic neprilysin family: P08473|NEP_HUMAN neprilysin (749 aa), FASTA scores: opt: 872, E(): 0, (31.1% identity in 692 aa overlap); Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus lactis (626 aa), FASTA scores: opt: 862,E(): 0, (30.0% identity in 654 aa overlap). Contains PS00142 Neutral zinc metallopept [...] | 0.407 |
PPE29 | PE_PGRS46 | Rv1801 | Rv2634c | PPE family protein PPE29; Could be required for host endothelial-cell invasion and/or intracellular survival; Belongs to the mycobacterial PPE family. | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.548 |
PPE67 | PE2 | Rv3739c | Rv0152c | Rv3739c, (MTV025.087c), len: 77 aa. PPE67, Member of the Mycobacterium tuberculosis PE family, showing high homology with O53269|Rv3022c|MTV012.36c (82 aa) FASTA scores: opt: 398, E(): 1.2e-19, (74.0% identity in 77 aa overlap); and similar to the N-termini of other PPE proteins e.g. O53265|Rv3018c|MTV012.32c (434 aa) FASTA scores: opt: 398, E(): 4.8e-19, (74.0% identity in 77 aa overlap). ORF ends at the stop codon at position 97470,which is not present in similar ORFs: MTV012_32, or MTCY21B4_4. Sequence homology with MTV012_32, and MTCY21B4_4 continues in the downstream ORF MTV025.08 [...] | Rv0152c, (MTCI5.26c), len: 525 aa. PE2, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to ORF downstream Z92770|MTCI5_25 (588 aa),FASTA scores: opt: 1492, E(): 0, (54.7% identity in 464 aa overlap); and to many other PE family type members. Predicted to be an outer membrane protein (See Song et al.,2008). | 0.454 |
PPE67 | PE_PGRS46 | Rv3739c | Rv2634c | Rv3739c, (MTV025.087c), len: 77 aa. PPE67, Member of the Mycobacterium tuberculosis PE family, showing high homology with O53269|Rv3022c|MTV012.36c (82 aa) FASTA scores: opt: 398, E(): 1.2e-19, (74.0% identity in 77 aa overlap); and similar to the N-termini of other PPE proteins e.g. O53265|Rv3018c|MTV012.32c (434 aa) FASTA scores: opt: 398, E(): 4.8e-19, (74.0% identity in 77 aa overlap). ORF ends at the stop codon at position 97470,which is not present in similar ORFs: MTV012_32, or MTCY21B4_4. Sequence homology with MTV012_32, and MTCY21B4_4 continues in the downstream ORF MTV025.08 [...] | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.543 |
Rv2633c | PE_PGRS46 | Rv2633c | Rv2634c | Hypothetical protein; Rv2633c, (MTCY441.03c), len: 161 aa. Hypothetical unknown protein. | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.444 |
Rv2635 | PE_PGRS46 | Rv2635 | Rv2634c | Hypothetical protein; Rv2635, (MTCY441.05), len: 80 aa. Hypothetical unknown protein. | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.575 |
Rv2635 | Rv2636 | Rv2635 | Rv2636 | Hypothetical protein; Rv2635, (MTCY441.05), len: 80 aa. Hypothetical unknown protein. | Rv2636, (MTCY441.06), len: 225 aa. Conserved hypothetical protein, showing some similarity with various proteins: Q98FG2|MLL3789 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (239 aa), FASTA scores: opt: 304, E(): 3.7e-13, (31.55% identity in 187 aa overlap); CAC46568|SMC04451 putative chloramphenicol phosphotransferase protein from Rhizobium meliloti (Sinorhizobium meliloti) (220 aa), FASTA scores: opt: 175,E(): 0.00014, (28.0% identity in 225 aa overlap); Q56148|CPT_STRVL chloramphenicol 3-O phosphotransferase from Streptomyces violaceus (Streptomyces venezuelae) (178 [...] | 0.775 |
Rv2636 | PE_PGRS46 | Rv2636 | Rv2634c | Rv2636, (MTCY441.06), len: 225 aa. Conserved hypothetical protein, showing some similarity with various proteins: Q98FG2|MLL3789 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (239 aa), FASTA scores: opt: 304, E(): 3.7e-13, (31.55% identity in 187 aa overlap); CAC46568|SMC04451 putative chloramphenicol phosphotransferase protein from Rhizobium meliloti (Sinorhizobium meliloti) (220 aa), FASTA scores: opt: 175,E(): 0.00014, (28.0% identity in 225 aa overlap); Q56148|CPT_STRVL chloramphenicol 3-O phosphotransferase from Streptomyces violaceus (Streptomyces venezuelae) (178 [...] | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.568 |
Rv2636 | Rv2635 | Rv2636 | Rv2635 | Rv2636, (MTCY441.06), len: 225 aa. Conserved hypothetical protein, showing some similarity with various proteins: Q98FG2|MLL3789 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (239 aa), FASTA scores: opt: 304, E(): 3.7e-13, (31.55% identity in 187 aa overlap); CAC46568|SMC04451 putative chloramphenicol phosphotransferase protein from Rhizobium meliloti (Sinorhizobium meliloti) (220 aa), FASTA scores: opt: 175,E(): 0.00014, (28.0% identity in 225 aa overlap); Q56148|CPT_STRVL chloramphenicol 3-O phosphotransferase from Streptomyces violaceus (Streptomyces venezuelae) (178 [...] | Hypothetical protein; Rv2635, (MTCY441.05), len: 80 aa. Hypothetical unknown protein. | 0.775 |
zmp1 | PE_PGRS46 | Rv0198c | Rv2634c | Rv0198c, (MTV033.06c), len: 663 aa. Probable zmp1,zinc metalloprotease, equivalent to Z95398|MLCL622.12c from Mycobacterium leprae (667 aa), FASTA scores: opt: 3710,E(): 0, (80.8 % identity in 667 aa overlap). Also similar to many other metalloproteases e.g. members of the eukaryotic neprilysin family: P08473|NEP_HUMAN neprilysin (749 aa), FASTA scores: opt: 872, E(): 0, (31.1% identity in 692 aa overlap); Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus lactis (626 aa), FASTA scores: opt: 862,E(): 0, (30.0% identity in 654 aa overlap). Contains PS00142 Neutral zinc metallopept [...] | PE-PGRS family protein PE_PGRS46; Rv2634c, (MTCY441.04c), len: 778 aa. PE_PGRS46,Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), highly similar to many e.g. O53553|YZ08_MYCTU|Rv3508|MTV023.15 from Mycobacterium tuberculosis (1901 aa), FASTA scores: opt: 2553, E(): 2.2e-93, (53.8% identity in 866 aa overlap). Equivalent to AAK47026 from Mycobacterium tuberculosis strain CDC1551 (788 aa) but shorter 10 aa. | 0.407 |