node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv2645 | Rv2659c | Rv2645 | Rv2659c | Hypothetical protein; Rv2645, (MTCY441.15), len: 143 aa. Hypothetical unknown protein. | Probable PhiRv2 prophage integrase; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome (By similarity). | 0.660 |
Rv2645 | Rv2661c | Rv2645 | Rv2661c | Hypothetical protein; Rv2645, (MTCY441.15), len: 143 aa. Hypothetical unknown protein. | Hypothetical protein; Rv2661c, (MTCY441.30c), len: 129 aa. Hypothetical unknown protein. | 0.871 |
Rv2645 | korB | Rv2645 | Rv2454c | Hypothetical protein; Rv2645, (MTCY441.15), len: 143 aa. Hypothetical unknown protein. | Probable oxidoreductase (beta subunit); Component of KG oxidoreductase (KOR) that catalyzes the CoA- dependent oxidative decarboxylation of 2-oxoglutarate (alpha- ketoglutarate, KG) to succinyl-CoA. Methyl viologen can act as electron acceptor in vitro; the physiologic electron acceptor is unknown. Is involved in the alternative TCA pathway that functions concurrently with fatty acid beta-oxidation. Since a growing body of evidence indicates that lipids (for example cholesterol and fatty acids) are a predominant growth substrate for M.tuberculosis during infection, flux through KOR lik [...] | 0.439 |
Rv2654c | Rv2655c | Rv2654c | Rv2655c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | 0.784 |
Rv2654c | Rv2656c | Rv2654c | Rv2656c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Possible PhiRv2 prophage protein; Rv2656c, (MTCY441.25c), len: 130 aa. Probable phiRv2 phage protein (see Hatfull 2000), highly similar to O06607|YF83_MYCTU|Rv1583c|MT3573.2|MTCY336.21 Probable phiRV1 phage protein from Mycobacterium tuberculosis (132 aa), FASTA scores: opt: 734, E(): 2.5e-39, (81.5% identity in 131 aa overlap); and some similarity with Q982T4|MLL8506 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (204 aa), FASTA scores: opt: 104, E(): 9.7, (31.85% identity in 113 aa overlap); To M.tuberculosis Rv1583c. | 0.921 |
Rv2654c | Rv2657c | Rv2654c | Rv2657c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Rv2657c, (MTCY441.26c), len: 86 aa. Probable phiRv2 phage protein (excisionase) (see citation below), similar to O22001|VG36_BPMD2|36|G2 gene 36 protein (GP36) from Mycobacteriophage D29 (56 aa), FASTA scores: opt: 171, E(): 9.6e-06, (48.0% identity in 50 aa overlap); and Q05246|VG36_BPML5|36 gene 36 protein (GP36) from Mycobacteriophage L5 (56 aa), FASTA scores: opt: 169, E(): 1.3e-05, (50% identity in 50 aa overlap). Similarity suggests alternative start at 21737. Contains possible helix-turn-helix motif from aa 33 to 54 (Score 1655, +4.82 SD). | 0.896 |
Rv2654c | Rv2658c | Rv2654c | Rv2658c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Possible prophage protein; Rv2658c, (MTCY441.27c), len: 120 aa. Hypothetical unknown protein, probably phage protein. | 0.852 |
Rv2654c | Rv2659c | Rv2654c | Rv2659c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Probable PhiRv2 prophage integrase; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome (By similarity). | 0.815 |
Rv2654c | Rv2660c | Rv2654c | Rv2660c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Hypothetical protein; Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein. | 0.476 |
Rv2654c | Rv2661c | Rv2654c | Rv2661c | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | Hypothetical protein; Rv2661c, (MTCY441.30c), len: 129 aa. Hypothetical unknown protein. | 0.462 |
Rv2655c | Rv2654c | Rv2655c | Rv2654c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | 0.784 |
Rv2655c | Rv2656c | Rv2655c | Rv2656c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Possible PhiRv2 prophage protein; Rv2656c, (MTCY441.25c), len: 130 aa. Probable phiRv2 phage protein (see Hatfull 2000), highly similar to O06607|YF83_MYCTU|Rv1583c|MT3573.2|MTCY336.21 Probable phiRV1 phage protein from Mycobacterium tuberculosis (132 aa), FASTA scores: opt: 734, E(): 2.5e-39, (81.5% identity in 131 aa overlap); and some similarity with Q982T4|MLL8506 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (204 aa), FASTA scores: opt: 104, E(): 9.7, (31.85% identity in 113 aa overlap); To M.tuberculosis Rv1583c. | 0.831 |
Rv2655c | Rv2657c | Rv2655c | Rv2657c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Rv2657c, (MTCY441.26c), len: 86 aa. Probable phiRv2 phage protein (excisionase) (see citation below), similar to O22001|VG36_BPMD2|36|G2 gene 36 protein (GP36) from Mycobacteriophage D29 (56 aa), FASTA scores: opt: 171, E(): 9.6e-06, (48.0% identity in 50 aa overlap); and Q05246|VG36_BPML5|36 gene 36 protein (GP36) from Mycobacteriophage L5 (56 aa), FASTA scores: opt: 169, E(): 1.3e-05, (50% identity in 50 aa overlap). Similarity suggests alternative start at 21737. Contains possible helix-turn-helix motif from aa 33 to 54 (Score 1655, +4.82 SD). | 0.800 |
Rv2655c | Rv2658c | Rv2655c | Rv2658c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Possible prophage protein; Rv2658c, (MTCY441.27c), len: 120 aa. Hypothetical unknown protein, probably phage protein. | 0.747 |
Rv2655c | Rv2659c | Rv2655c | Rv2659c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Probable PhiRv2 prophage integrase; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome (By similarity). | 0.819 |
Rv2655c | Rv2660c | Rv2655c | Rv2660c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Hypothetical protein; Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein. | 0.469 |
Rv2655c | Rv2661c | Rv2655c | Rv2661c | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | Hypothetical protein; Rv2661c, (MTCY441.30c), len: 129 aa. Hypothetical unknown protein. | 0.464 |
Rv2656c | Rv2654c | Rv2656c | Rv2654c | Possible PhiRv2 prophage protein; Rv2656c, (MTCY441.25c), len: 130 aa. Probable phiRv2 phage protein (see Hatfull 2000), highly similar to O06607|YF83_MYCTU|Rv1583c|MT3573.2|MTCY336.21 Probable phiRV1 phage protein from Mycobacterium tuberculosis (132 aa), FASTA scores: opt: 734, E(): 2.5e-39, (81.5% identity in 131 aa overlap); and some similarity with Q982T4|MLL8506 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (204 aa), FASTA scores: opt: 104, E(): 9.7, (31.85% identity in 113 aa overlap); To M.tuberculosis Rv1583c. | Possible PhiRv2 prophage protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv2653c. | 0.921 |
Rv2656c | Rv2655c | Rv2656c | Rv2655c | Possible PhiRv2 prophage protein; Rv2656c, (MTCY441.25c), len: 130 aa. Probable phiRv2 phage protein (see Hatfull 2000), highly similar to O06607|YF83_MYCTU|Rv1583c|MT3573.2|MTCY336.21 Probable phiRV1 phage protein from Mycobacterium tuberculosis (132 aa), FASTA scores: opt: 734, E(): 2.5e-39, (81.5% identity in 131 aa overlap); and some similarity with Q982T4|MLL8506 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (204 aa), FASTA scores: opt: 104, E(): 9.7, (31.85% identity in 113 aa overlap); To M.tuberculosis Rv1583c. | Possible PhiRv2 prophage protein; Rv2655c, (MTCY441.24c), len: 475 aa. Hypothetical protein, possibly phiRv2 phage protein (putative primase-like protein) (see citation below). C-terminus similar to P22875|YXIS_SACER hypothetical 28.9 KDA protein (probably does not play a direct role in plasmid integration or excision) from Saccharopolyspora erythraea (Streptomyces erythraeus) plasmid pSE211 (263 aa), FASTA scores: opt: 389, E(): 2.7e-15, (33.45% identity in 269 aa overlap). Weak similarity in N-terminus to O06608|MTCY336.22|Rv1582c Probable phiRV1 phage protein from Mycobacterium tube [...] | 0.831 |
Rv2656c | Rv2657c | Rv2656c | Rv2657c | Possible PhiRv2 prophage protein; Rv2656c, (MTCY441.25c), len: 130 aa. Probable phiRv2 phage protein (see Hatfull 2000), highly similar to O06607|YF83_MYCTU|Rv1583c|MT3573.2|MTCY336.21 Probable phiRV1 phage protein from Mycobacterium tuberculosis (132 aa), FASTA scores: opt: 734, E(): 2.5e-39, (81.5% identity in 131 aa overlap); and some similarity with Q982T4|MLL8506 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (204 aa), FASTA scores: opt: 104, E(): 9.7, (31.85% identity in 113 aa overlap); To M.tuberculosis Rv1583c. | Rv2657c, (MTCY441.26c), len: 86 aa. Probable phiRv2 phage protein (excisionase) (see citation below), similar to O22001|VG36_BPMD2|36|G2 gene 36 protein (GP36) from Mycobacteriophage D29 (56 aa), FASTA scores: opt: 171, E(): 9.6e-06, (48.0% identity in 50 aa overlap); and Q05246|VG36_BPML5|36 gene 36 protein (GP36) from Mycobacteriophage L5 (56 aa), FASTA scores: opt: 169, E(): 1.3e-05, (50% identity in 50 aa overlap). Similarity suggests alternative start at 21737. Contains possible helix-turn-helix motif from aa 33 to 54 (Score 1655, +4.82 SD). | 0.924 |