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Rv3047c Rv3047c nrdF2 nrdF2 Rv2898c Rv2898c Rv2325c Rv2325c Rv1706A Rv1706A Rv1382 Rv1382 PPE23 PPE23 ftsE ftsE recX recX Rv3046c Rv3046c
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
Rv3047cHypothetical protein; Rv3047c, (MTV012.62c), len: 94 aa. Hypothetical unknown protein. (94 aa)    
Predicted Functional Partners:
nrdF2
Ribonucleoside-diphosphate reductase subunit beta nrdF2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Two genes for this protein are present in M.tuberculosis; this is the active form. When coexpressed in E.coli with nrdE the 2 proteins complement a temperature-sensitive E.coli mutant; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
    0.935
Rv2898c
Rv2898c, (MTCY274.29c), len: 128 aa. Conserved hypothetical protein, highly similar to O33024|YS98_MYCLE|ML1607|MLCB250.49 hypothetical 11.0 KDA protein from Mycobacterium leprae (96 aa), FASTA scores: opt: 318, E(): 2.3e-16, (58.35% identity in 96 aa overlap). Also similar to other hypothetical proteins e.g. O69890|YE19_STRCO|SC2E1.19 from Streptomyces coelicolor (130 aa), FASTA scores: opt: 253, E(): 1.7e-11, (39.65% identity in 121 aa overlap); Q9HVZ1|PA4424 from Pseudomonas aeruginosa (125 aa), FASTA scores: opt: 234, E(): 4.2e-10,(40.85% identity in 115 aa overlap); O86871 from St [...]
   
  
 0.809
Rv2325c
Rv2325c, (MTCY3G12.09), len: 282 aa. Conserved hypothetical protein, equivalent to O32970|MLCB22.37c|ML0849 hypothetical protein from Mycobacterium leprae (283 aa), FASTA scores: opt: 1405,E(): 1.8e-78, (77.7% identity in 282 aa overlap). Also some similarity to other proteins e.g. Q9Z9J1|YBAF|BH0166 YBAF protein (BH0166 protein) (hypothetical protein) from Bacillus halodurans (265 aa), FASTA scores: opt: 288, E(): 2.8e-10, (25.8% identity in 264 aa overlap); P70972|YBAF YBAF protein (hypothetical protein) from Bacillus subtilis (265 aa), FASTA scores: opt: 259, E(): 1.5e-08, (25.45% i [...]
   
  
 0.808
Rv1706A
Rv1706A, len: 55 aa. Conserved hypothetical protein,similar to part of several probable export proteins e.g. Rv0783c|Z80226_28 from Mycobacterium tuberculosis (540 aa),FASTA scores: opt: 125, E(): 0.011, (52.85% identity in 53 aa overlap). Size difference suggests possible gene fragment.
   
  
 0.804
Rv1382
Rv1382, (MTCY02B12.16), len: 165 aa. Possible exported or membrane protein, hydrophobic domain at N-terminus. Predicted to be an outer membrane protein (See Song et al., 2008).
      
 0.803
PPE23
Rv1706c, (MTCI125.28c), len: 394 aa. PPE23, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, similar to many e.g. YX23_MYCTU|Q10813 hypothetical 41.1 kDa protein cy274.23 (404 aa), fasta scores: opt: 841, E(): 3.9e-31, (46.8% identity in 408 aa overlap).
   
  
 0.659
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. Has ATPase activity.
   
  
 0.651
recX
Regulatory protein RecX; Binds to RecA inhibiting ATP hydrolysis and the generation of heteroduplex DNA. It might act as an anti-recombinase to quell inappropriate recombinational repair during normal DNA metabolism. It is essential for cell survival; Belongs to the RecX family.
   
  
 0.518
Rv3046c
Conserved protein; Rv3046c, (MTV012.61c), len: 124 aa. Conserved protein, similar to several hypothetical mycobacterial proteins e.g. Q50171|ML2258 U296W hypothetical protein from Mycobacterium leprae (100 aa), FASTA scores: opt: 194, E(): 7.6e-06, (35.9% identity in 103 aa overlap); and O06409|Rv0543c|MTCY25D10.22c from Mycobacterium tuberculosis (100 aa), FASTA scores: opt: 192, E(): 1e-05,(34.7% identity in 98 aa overlap).
       0.416
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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