STRINGSTRING
Rv3191c Rv3191c TB7.3 TB7.3 rsmH rsmH ilvB1 ilvB1 frr frr Rv2621c Rv2621c Rv2618 Rv2618
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rv3191cProbable transposase; Rv3191c, (MTV014.35c), len: 344 aa. Probable transposase, similar to many especially Q9K2N8 putative transposase from Pseudomonas aeruginosa (338 aa), FASTA scores: opt: 837, E(): 1.3e-43, (42.55% identity in 336 aa overlap); Q9RBF4 insertion sequence IS1088 from Alcaligenes eutrophus (Ralstonia eutropha) (342 aa), FASTA scores: opt: 823, E(): 9.2e-43, (43.05% identity in 337 aa overlap); and Q51379 putative transposase from Pseudomonas alcaligenes (338 aa), FASTA scores: opt: 818, E(): 1.8e-42, (42.35% identity in 333 aa overlap). Contains probable helix-turn-hel [...] (344 aa)    
Predicted Functional Partners:
TB7.3
Biotinylated protein TB7.3; Rv3221c, (MTCY07D11.05), len: 71 aa. TB7.3,Biotinylated protein (see citations below), equivalent (appears to have one additional residue) to Q9CCH9|ML0802|BTB7_MYCLE biotinylated protein TB7.3 homolog from Mycobacterium leprae (70 aa), FASTA scores: opt: 367,E(): 4e-18, (90.0% identity in 70 aa overlap); Q9XCD6|BTB7_MYCSM biotinylated protein TB7.3 homolog from Mycobacterium smegmatis (70 aa), FASTA scores: opt: 341,E(): 2.1e-16, (84.05% identity in 69 aa overlap). Similar to C-terminal part of various proteins e.g. Q9HPP8|ACC|VNG1532G biotin carboxylase fr [...]
   
  
 0.545
rsmH
Conserved protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA; Belongs to the methyltransferase superfamily. RsmH family.
      
 0.540
ilvB1
Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase); Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine. Also involved in condensing pyruvate and 2-ketobutyrate to form 2-aceto-2- hydroxybutyrate.
   
  
 0.442
frr
Ribosome recycling factor Frr (ribosome releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
   
  
 0.439
Rv2621c
Rv2621c, (MTCY01A10.11), len: 224 aa. Possible transcriptional regulator, similar in part to Q49688|MLCL536.29c|ML0592 putative DNA-binding protein from Mycobacterium leprae (254 aa), FASTA scores: opt: 168, E(): 0.0018, (29.75% identity in 222 aa overlap). Shows similarity with Q9XAD0|SCC22.08c putative DNA-binding protein from Streptomyces coelicolor (252 aa), FASTA scores: opt: 148, E(): 0.032, (29.4% identity in 204 aa overlap); and Q9RVM8|DR0999 conserved hypothetical protein from Deinococcus radiodurans (225 aa), FASTA scores: opt: 195, E(): 3.3e-05, (29.6% identity in 213 aa ove [...]
   
  
 0.436
Rv2618
Rv2618, (MTCY01A10.15c), len: 225 aa. Conserved hypothetical protein, similar in part to Q9EWQ9|SC4C2.03 conserved hypothetical protein from Streptomyces coelicolor (159 aa), FASTA scores: opt: 235, E(): 1.3e-07, (43.7% identity in 103 aa overlap); Q9HLM6|TA0201 hypothetical protein from Thermoplasma acidophilum (215 aa), FASTA scores: opt: 164, E(): 0.0038, (23.4% identity in 201 aa overlap); and to mycobacterial proteins e.g. O06191|Rv2621c|MTCY01A10.11 hypothetical 24.2 KDA protein from Mycobacterium tuberculosis (224 aa), FASTA scores: opt: 149, E(): 0.033, (28.05% identity in 196 [...]
      
 0.434
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
Server load: low (28%) [HD]