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There are several matches for 'Rv3425'.
Please select one from the list below and press Continue to proceed.
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organism
protein
1)
Mycobacterium tuberculosis H37Rv
PPE57 - PPE family protein PPE57; Plays a key role in regulating innate and adaptive immune responses through human Toll-like receptor 2 (TLR2). Interacts with TLR2, leading to the subsequent activation of the mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-kappa-B) signaling pathways. Induces macrophage activation by augmenting the expression of several cell surface molecules (CD40, CD80, CD86 and MHC class II) and pro-inflammatory cytokines (TNF-alpha, IL-6 and IL-12p40) within macrophages. Also participates in adaptive immunity by directing Th1- polarised immune respo [...]
[a.k.a.
Rv3425
, CCP46247.1, NZ_NVQJ01000027.1]
2)
Mycobacterium tuberculosis H37Rv
PPE58 - Rv3426, (MTCY78.03c), len: 232 aa. PPE58, Member of the M. tuberculosis PPE family, similar to many e.g. the downstream O06246|Rv3429|MTCY77.01 (178 aa), FASTA scores: opt: 555, E(): 6.5e-26, (72.0% identity in 125 aa overlap); and upstream Q50703|YY25_MYCTU|
Rv3425
|MTCY78.04c (176 aa),FASTA scores: opt: 517, E(): 1.1e-23, (68.0% identity in 125 aa overlap); MTV049_30, MTCY3C7_24, MTCY428_16,MTCY3A2_22; etc.
[a.k.a. Rv3426, CCP46248.1, RVBD_3426]
3)
Mycobacterium tuberculosis H37Rv
PPE59 - Rv3429, (MTCY77.01), len: 178 aa. PPE59, Member of the M. tuberculosis PPE family, similar to many e.g. the upstream Q50703|YY25_MYCTU|
Rv3425
|MTCY78.04c (176 aa),FASTA scores: opt: 781, E(): 1.9e-44, (69.9% identity in 176 aa overlap); and Q50702|YY26_MYCTU|Rv3426|MTCY78.03c (232 aa), FASTA scores: opt: 555, E(): 1.7e-29, (72.0% identity in 125 aa overlap) (but diverges at 3' end); etc.
[a.k.a. CCP46251.1, Rv3429, L0TFC8]