node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PE_PGRS53 | PE_PGRS54 | Rv3507 | Rv3508 | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | PE-PGRS family protein PE_PGRS54; Rv3508, (MTV023.15), len: 1901 aa. PE_PGRS54, Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see Brennan & Delogu 2002), similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. downstream O53559|Rv3514|MTV023.21 (1489 aa),FASTA scores: opt: 6598, E(): 0, (71.05% identity in 1533 aa overlap). Equivalent to AAK47971 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but shorter 13 aa and with some minor differences between the proteins. Contains five PS00583 pfkB family of carbohydr [...] | 0.433 |
PE_PGRS53 | PE_PGRS56 | Rv3507 | Rv3512 | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | PE-PGRS family protein PE_PGRS56; Rv3512, (MTV023.19), len: 1079 aa. PE_PGRS56, Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. AAK47974|MT3615.3 (1217 aa) FASTA scores: opt: 3688, E(): 4.5e-130, (53.95% identity in 1136 aa overlap); and downstream O53559|Rv3514|MTV023.21 (1489 aa), FASTA scores: opt: 3611, E(): 3.6e-127, (53.15% identity in 1195 aa overlap); etc. Frameshifted PGRS protein, could be continuation of upstream MTV023.18, but no err [...] | 0.511 |
PE_PGRS53 | fadD17 | Rv3507 | Rv3506 | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase); Catalyzes the activation of long-chain fatty acids as acyl- coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. | 0.464 |
PE_PGRS53 | zmp1 | Rv3507 | Rv0198c | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | Rv0198c, (MTV033.06c), len: 663 aa. Probable zmp1,zinc metalloprotease, equivalent to Z95398|MLCL622.12c from Mycobacterium leprae (667 aa), FASTA scores: opt: 3710,E(): 0, (80.8 % identity in 667 aa overlap). Also similar to many other metalloproteases e.g. members of the eukaryotic neprilysin family: P08473|NEP_HUMAN neprilysin (749 aa), FASTA scores: opt: 872, E(): 0, (31.1% identity in 692 aa overlap); Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus lactis (626 aa), FASTA scores: opt: 862,E(): 0, (30.0% identity in 654 aa overlap). Contains PS00142 Neutral zinc metallopept [...] | 0.407 |
PE_PGRS54 | PE_PGRS53 | Rv3508 | Rv3507 | PE-PGRS family protein PE_PGRS54; Rv3508, (MTV023.15), len: 1901 aa. PE_PGRS54, Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see Brennan & Delogu 2002), similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. downstream O53559|Rv3514|MTV023.21 (1489 aa),FASTA scores: opt: 6598, E(): 0, (71.05% identity in 1533 aa overlap). Equivalent to AAK47971 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but shorter 13 aa and with some minor differences between the proteins. Contains five PS00583 pfkB family of carbohydr [...] | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | 0.433 |
PE_PGRS54 | zmp1 | Rv3508 | Rv0198c | PE-PGRS family protein PE_PGRS54; Rv3508, (MTV023.15), len: 1901 aa. PE_PGRS54, Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see Brennan & Delogu 2002), similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. downstream O53559|Rv3514|MTV023.21 (1489 aa),FASTA scores: opt: 6598, E(): 0, (71.05% identity in 1533 aa overlap). Equivalent to AAK47971 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but shorter 13 aa and with some minor differences between the proteins. Contains five PS00583 pfkB family of carbohydr [...] | Rv0198c, (MTV033.06c), len: 663 aa. Probable zmp1,zinc metalloprotease, equivalent to Z95398|MLCL622.12c from Mycobacterium leprae (667 aa), FASTA scores: opt: 3710,E(): 0, (80.8 % identity in 667 aa overlap). Also similar to many other metalloproteases e.g. members of the eukaryotic neprilysin family: P08473|NEP_HUMAN neprilysin (749 aa), FASTA scores: opt: 872, E(): 0, (31.1% identity in 692 aa overlap); Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus lactis (626 aa), FASTA scores: opt: 862,E(): 0, (30.0% identity in 654 aa overlap). Contains PS00142 Neutral zinc metallopept [...] | 0.407 |
PE_PGRS56 | PE_PGRS53 | Rv3512 | Rv3507 | PE-PGRS family protein PE_PGRS56; Rv3512, (MTV023.19), len: 1079 aa. PE_PGRS56, Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see citation below), similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. AAK47974|MT3615.3 (1217 aa) FASTA scores: opt: 3688, E(): 4.5e-130, (53.95% identity in 1136 aa overlap); and downstream O53559|Rv3514|MTV023.21 (1489 aa), FASTA scores: opt: 3611, E(): 3.6e-127, (53.15% identity in 1195 aa overlap); etc. Frameshifted PGRS protein, could be continuation of upstream MTV023.18, but no err [...] | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | 0.511 |
fadD17 | PE_PGRS53 | Rv3506 | Rv3507 | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase); Catalyzes the activation of long-chain fatty acids as acyl- coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | 0.464 |
zmp1 | PE_PGRS53 | Rv0198c | Rv3507 | Rv0198c, (MTV033.06c), len: 663 aa. Probable zmp1,zinc metalloprotease, equivalent to Z95398|MLCL622.12c from Mycobacterium leprae (667 aa), FASTA scores: opt: 3710,E(): 0, (80.8 % identity in 667 aa overlap). Also similar to many other metalloproteases e.g. members of the eukaryotic neprilysin family: P08473|NEP_HUMAN neprilysin (749 aa), FASTA scores: opt: 872, E(): 0, (31.1% identity in 692 aa overlap); Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus lactis (626 aa), FASTA scores: opt: 862,E(): 0, (30.0% identity in 654 aa overlap). Contains PS00142 Neutral zinc metallopept [...] | PE-PGRS family protein PE_PGRS53; Rv3507, (MTV023.14), len: 1381 aa. PE_PGRS53, Member of the Mycobacterium tuberculosis PE protein family, PGRS subfamily of gly-rich proteins (see citation below),similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O06810|Rv1450c|MTCY493.04 (1329 aa),FASTA scores: opt: 2173, E(): 1.4e-135, (51.15% identity in 1412 aa overlap). Equivalent to AAK47970 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but with some minor differences between the proteins. Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. | 0.407 |
zmp1 | PE_PGRS54 | Rv0198c | Rv3508 | Rv0198c, (MTV033.06c), len: 663 aa. Probable zmp1,zinc metalloprotease, equivalent to Z95398|MLCL622.12c from Mycobacterium leprae (667 aa), FASTA scores: opt: 3710,E(): 0, (80.8 % identity in 667 aa overlap). Also similar to many other metalloproteases e.g. members of the eukaryotic neprilysin family: P08473|NEP_HUMAN neprilysin (749 aa), FASTA scores: opt: 872, E(): 0, (31.1% identity in 692 aa overlap); Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus lactis (626 aa), FASTA scores: opt: 862,E(): 0, (30.0% identity in 654 aa overlap). Contains PS00142 Neutral zinc metallopept [...] | PE-PGRS family protein PE_PGRS54; Rv3508, (MTV023.15), len: 1901 aa. PE_PGRS54, Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins (see Brennan & Delogu 2002), similar to others from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. downstream O53559|Rv3514|MTV023.21 (1489 aa),FASTA scores: opt: 6598, E(): 0, (71.05% identity in 1533 aa overlap). Equivalent to AAK47971 from Mycobacterium tuberculosis strain CDC1551 (1384 aa) but shorter 13 aa and with some minor differences between the proteins. Contains five PS00583 pfkB family of carbohydr [...] | 0.407 |