node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0760c | Rv3521 | Rv0760c | Rv3521 | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | 0.722 |
Rv0760c | Rv3527 | Rv0760c | Rv3527 | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | 0.703 |
Rv0760c | Rv3542c | Rv0760c | Rv3542c | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | Rv3542c, (MTCY03C7.14), len: 311 aa. Hypothetical protein, showing some similarity to other e.g. Q58947|MJ1552 from Methanococcus jannaschii (141 aa) FASTA scores: opt: 177, E(): 0.00065, (46.65% identity in 60 aa overlap); BAB59276|TVG0142586 from Thermoplasma volcanium (135 aa), FASTA scores: opt: 175, E(): 0.00083, (35.65% identity in 87 aa overlap); Q9HI85|TA1457 from Thermoplasma acidophilum (135 aa), FASTA scores: opt: 162, E(): 0.0052,(31.8% identity in 107 aa overlap); etc. | 0.682 |
Rv0760c | hsaC | Rv0760c | Rv3568c | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | 3,4-DHSA dioxygenase; Catalyzes the meta-cleavage of 3,4-dihydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) to produce 4,5- 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oic acid (4,9-DSHA). | 0.712 |
Rv0760c | kshA | Rv0760c | Rv3526 | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | Oxygenase component of 3-ketosteroid-9-alpha-hydroxylase KshA; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. KSH is also able to use 4- androstene-3,17-dione (AD), 3-oxo-23,24-bisnorcholesta-4-en-22-oate (4- BNC), 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oate (1,4 [...] | 0.736 |
Rv0760c | kstR | Rv0760c | Rv3574 | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | Transcriptional regulatory protein KstR (probably TetR-family); Controls the expression of genes used for utilizing diverse lipids as energy sources. | 0.525 |
Rv2743c | Rv3527 | Rv2743c | Rv3527 | Rv2743c, (MTV002.08c), len: 270 aa. Possible conserved transmembrane ala-rich protein, equivalent to Q49833|MLCB33.04c|B2235_C1_148 unknown protein from Mycobacterium leprae (123 aa), FASTA scores: opt: 639, E(): 3.3e-31, (74.8% identity in 123 aa overlap). | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | 0.736 |
Rv2743c | lpqE | Rv2743c | Rv3584 | Rv2743c, (MTV002.08c), len: 270 aa. Possible conserved transmembrane ala-rich protein, equivalent to Q49833|MLCB33.04c|B2235_C1_148 unknown protein from Mycobacterium leprae (123 aa), FASTA scores: opt: 639, E(): 3.3e-31, (74.8% identity in 123 aa overlap). | Rv3584, (MTV024.02), len: 182 aa. Possible lpqE,conserved lipoprotein, equivalent to Q9ZBM7|MLCB1450.02|LPQE|ML0319 putative lipoprotein from Mycobacterium leprae (183 aa), FASTA scores: opt: 722, E(): 6.2e-37, (63.45% identity in 175 aa overlap). Also similar in part to Q9KK69 exported protein 996A010 (fragment) from Mycobacterium avium (41 aa), FASTA scores: opt: 180, E(): 0.00012, (69.25% identity in 39 aa overlap); and Q9L0R0|SCD8A.04c putative lipoprotein from Streptomyces coelicolor (241 aa), FASTA scores: opt: 127, E(): 0.86,(27.15% identity in 173 aa overlap). Equivalent to AAK [...] | 0.634 |
Rv3521 | Rv0760c | Rv3521 | Rv0760c | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | 0.722 |
Rv3521 | Rv3527 | Rv3521 | Rv3527 | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | 0.733 |
Rv3521 | Rv3542c | Rv3521 | Rv3542c | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | Rv3542c, (MTCY03C7.14), len: 311 aa. Hypothetical protein, showing some similarity to other e.g. Q58947|MJ1552 from Methanococcus jannaschii (141 aa) FASTA scores: opt: 177, E(): 0.00065, (46.65% identity in 60 aa overlap); BAB59276|TVG0142586 from Thermoplasma volcanium (135 aa), FASTA scores: opt: 175, E(): 0.00083, (35.65% identity in 87 aa overlap); Q9HI85|TA1457 from Thermoplasma acidophilum (135 aa), FASTA scores: opt: 162, E(): 0.0052,(31.8% identity in 107 aa overlap); etc. | 0.784 |
Rv3521 | hsaC | Rv3521 | Rv3568c | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | 3,4-DHSA dioxygenase; Catalyzes the meta-cleavage of 3,4-dihydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) to produce 4,5- 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oic acid (4,9-DSHA). | 0.737 |
Rv3521 | kshA | Rv3521 | Rv3526 | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | Oxygenase component of 3-ketosteroid-9-alpha-hydroxylase KshA; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. KSH is also able to use 4- androstene-3,17-dione (AD), 3-oxo-23,24-bisnorcholesta-4-en-22-oate (4- BNC), 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oate (1,4 [...] | 0.774 |
Rv3521 | kstR | Rv3521 | Rv3574 | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | Transcriptional regulatory protein KstR (probably TetR-family); Controls the expression of genes used for utilizing diverse lipids as energy sources. | 0.771 |
Rv3525c | Rv3527 | Rv3525c | Rv3527 | Rv3525c, (MTCY3C7.31), len: 174 aa. Possible siderophore-binding protein, similar to ferripyochelin binding proteins (and related) e.g. Q9RSN5|DR2089 ferripyochelin-binding protein from Deinococcus radiodurans (240 aa), FASTA scores: opt: 472, E(): 3.3e-21, (46.9% identity in 162 aa overlap); O59257|PH1591 long hypothetical ferripyochelin binding protein from Pyrococcus horikoshii (173 aa), FASTA scores: opt: 431, E(): 6.7e-19,(40.0% identity in 170 aa overlap); Q9V158|FBP|PAB0393 ferripyochelin binding protein from Pyrococcus abyssi (173 aa), FASTA scores: opt: 429, E(): 8.9e-19, (39. [...] | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | 0.780 |
Rv3525c | kshA | Rv3525c | Rv3526 | Rv3525c, (MTCY3C7.31), len: 174 aa. Possible siderophore-binding protein, similar to ferripyochelin binding proteins (and related) e.g. Q9RSN5|DR2089 ferripyochelin-binding protein from Deinococcus radiodurans (240 aa), FASTA scores: opt: 472, E(): 3.3e-21, (46.9% identity in 162 aa overlap); O59257|PH1591 long hypothetical ferripyochelin binding protein from Pyrococcus horikoshii (173 aa), FASTA scores: opt: 431, E(): 6.7e-19,(40.0% identity in 170 aa overlap); Q9V158|FBP|PAB0393 ferripyochelin binding protein from Pyrococcus abyssi (173 aa), FASTA scores: opt: 429, E(): 8.9e-19, (39. [...] | Oxygenase component of 3-ketosteroid-9-alpha-hydroxylase KshA; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. KSH is also able to use 4- androstene-3,17-dione (AD), 3-oxo-23,24-bisnorcholesta-4-en-22-oate (4- BNC), 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oate (1,4 [...] | 0.780 |
Rv3527 | Rv0760c | Rv3527 | Rv0760c | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | Conserved protein; Rv0760c, (MTCY369.05), len: 139 aa. Conserved protein, similar to N-terminal part of Rv2042c conserved hypothetical protein from Mycobacterium tuberculosis (265 aa), FASTA scores: opt: 150, E(): 4.1e-05, (28.7% identity in 136 aa overlap). Belongs to the NTF2-like (nuclear transport factor 2) protein superfamiily. | 0.703 |
Rv3527 | Rv2743c | Rv3527 | Rv2743c | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | Rv2743c, (MTV002.08c), len: 270 aa. Possible conserved transmembrane ala-rich protein, equivalent to Q49833|MLCB33.04c|B2235_C1_148 unknown protein from Mycobacterium leprae (123 aa), FASTA scores: opt: 639, E(): 3.3e-31, (74.8% identity in 123 aa overlap). | 0.736 |
Rv3527 | Rv3521 | Rv3527 | Rv3521 | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | Rv3521, (MTV023.28), len: 303 aa. Conserved hypothetical protein, similar to (although longer than) other conserved hypothetical proteins e.g. O29296|AF0966 from Archaeoglobus fulgidus (176 aa), FASTA scores: opt: 286, E(): 5.4e-11, (31.15% identity in 170 aa overlap); O30036|AF0203 from Archaeoglobus fulgidus (149 aa) FASTA scores: opt: 259, E(): 2.3e-09, (33.8% identity in 142 aa overlap); O29297|AF0965 from Archaeoglobus fulgidus (154 aa), FASTA scores: opt: 241, E(): 3.2e-08, (31.4% identity in 137 aa overlap); Q9Y995|APE2390 from Aeropyrum pernix (157 aa), FASTA scores: opt: 204, [...] | 0.733 |
Rv3527 | Rv3525c | Rv3527 | Rv3525c | Hypothetical protein; Rv3527, (MTCY03C7.29c), len: 149 aa. Hypothetical unknown protein. | Rv3525c, (MTCY3C7.31), len: 174 aa. Possible siderophore-binding protein, similar to ferripyochelin binding proteins (and related) e.g. Q9RSN5|DR2089 ferripyochelin-binding protein from Deinococcus radiodurans (240 aa), FASTA scores: opt: 472, E(): 3.3e-21, (46.9% identity in 162 aa overlap); O59257|PH1591 long hypothetical ferripyochelin binding protein from Pyrococcus horikoshii (173 aa), FASTA scores: opt: 431, E(): 6.7e-19,(40.0% identity in 170 aa overlap); Q9V158|FBP|PAB0393 ferripyochelin binding protein from Pyrococcus abyssi (173 aa), FASTA scores: opt: 429, E(): 8.9e-19, (39. [...] | 0.780 |