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Rv3689 Rv3689 Rv3690 Rv3690 Rv3691 Rv3691 Rv3693 Rv3693 moxR2 moxR2 Rv3695 Rv3695 Rv3694c Rv3694c Rv1616 Rv1616 Rv3688c Rv3688c Rv1870c Rv1870c Rv2585c Rv2585c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Rv3689Rv3689, (MTV025.037), len: 451 aa. Probable conserved transmembrane protein, with Proline rich N-terminus, similar to Q9KYW6|SCE33.17 putative integral membrane protein from Streptomyces coelicolor (462 aa) FASTA scores: opt: 730, E(): 2.7e-21, (38.1% identity in 412 aa overlap). (451 aa)    
Predicted Functional Partners:
Rv3690
Rv3690, (MTV025.038), len: 217 aa. Probable conserved membrane protein, similar to Q9KYW5|SCE33.18 putative integral membrane protein from Streptomyces coelicolor (231 aa), FASTA scores: opt: 419, E(): 1.5e-19,(36.0% identity in 211 aa overlap). Equivalent to AAK48159 from Mycobacterium tuberculosis strain CDC1551 (233 aa) but shorter 16 aa.
 
    0.961
Rv3691
Conserved protein; Rv3691, (MTV025.039), len: 333 aa. Conserved protein, similar to Q9KYW4|SCE33.19 putative secreted protein from Streptomyces coelicolor (387 aa) FASTA scores: opt: 481, E(): 6e-23, (36.6% identity in 358 aa overlap). Equivalent to AAK48160 from Mycobacterium tuberculosis strain CDC1551 (381 aa) but shorter 48 aa.
 
    0.938
Rv3693
Possible conserved membrane protein; Rv3693, (MTV025.041), len: 440 aa (alternative start at 41910). Possible conserved membrane protein, similar to Q9KYW2|SCE33.21 putative lipoprotein from Streptomyces coelicolor (436 aa), FASTA scores: opt: 875, E(): 3.3e-46,(56.25% identity in 448 aa overlap); Q9AAN0|CC0567 hypothetical protein from Caulobacter crescentus (437 aa),FASTA scores: opt: 355, E(): 2.3e-14, (30.9% identity in 450 aa overlap); P73233|SLR2013 hypothetical 48.5 KDA protein from Synechocystis sp. strain PCC 6803 (435 aa),FASTA scores: opt: 340, E(): 1.9e-13, (29.7% identity [...]
 
    0.911
moxR2
Rv3692, (MTV025.040), len: 358 aa. Probable moxR2,methanol dehydrogenase regulatory protein, highly similar (generally longer at N-terminus) to Q9KYW3|SCE33.20 putative regulatory protein from Streptomyces coelicolor (329 aa), FASTA scores: opt: 1523, E(): 4.2e-74, (70.9% identity in 330 aa overlap); Q9Z538|SC9B2.21c putative regulatory protein from Streptomyces coelicolor (332 aa) FASTA scores: opt: 1008, E(): 1.1e-46, (50.8% identity in 313 aa overlap); Q9UZ67|MOXR-3|PAB0848 methanol dehydrogenase regulatory protein from Pyrococcus abyssi (314 aa), FASTA scores: opt: 989, E(): 1.1e-4 [...]
 
    0.782
Rv3695
Rv3695, (MTV025.043), len: 310 aa. Possible conserved membrane protein, equivalent, but longer 88 aa,to Q9CB83|ML2312 possible membrane protein from Mycobacterium leprae (196 aa), FASTA scores: opt: 898, E(): 5.2e-36, (71.05% identity in 190 aa overlap). Also highly similar to Q9KZM3|SCE34.02 putative integral membrane protein from Streptomyces coelicolor (318 aa), FASTA scores: opt: 740,E(): 2.4e-28, (43.25% identity in 319 aa overlap); and similar to P72718|SLR0254 hypothetical 30.4 KDA protein from Synechocystis sp. strain PCC 6803 (266 aa), FASTA scores: opt: 287, E(): 6.1e-07, (29 [...]
 
    0.771
Rv3694c
Rv3694c, (MTV025.042c), len: 330 aa. Possible conserved transmembrane protein, highly similar to Q9KZM4|SCE34.01c putative integral membrane protein from Streptomyces coelicolor (335 aa), FASTA scores: opt: 1113,E(): 2.5e-60, (51.5% identity in 334 aa overlap); and similar to Q9KEW6|BH0733 hypothetical protein from Bacillus halodurans (355 aa), FASTA scores: opt: 381, E(): 6.1e-16,(24.15% identity in 331 aa overlap); Q9AAM9|CC0568 hypothetical protein from Caulobacter crescentus (332 aa),FASTA scores: opt: 352, E(): 3.3e-14, (30.3% identity in 310 aa overlap); P74166|SLR1478 hypothetic [...]
 
    0.752
Rv1616
Conserved membrane protein; Rv1616, (MTCY01B2.08), len: 132 aa. Conserved membrane protein, with some similarity to other hypothetical proteins e.g. AL096884|SC4G6_9 from Streptomyces coelicolor cosmid 4G6 (148 aa), FASTA scores: opt: 245, E(): 1.7e-1 0, (36.7% identity in 128 aa overlap); Q55401|SLL0543 hypothetical 16.5 kDa protein from synechocystis SP (148 aa), FASTA scores: opt: 225, E(): 6.5e-10, (35.9% identity in 117 aa overlap). Has cysteine cluster and contains a rubredoxin signature (PS00202).
  
  
 0.689
Rv3688c
Conserved protein; Rv3688c, (MTV025.036c), len: 154 aa. Conserved protein, similar to other bacterial hypothetical proteins e.g. Q9X934|SCH66.02c from Streptomyces coelicolor (154 aa), FASTA scores: opt: 425, E(): 3.4e-19, (46.1% identity in 154 aa overlap); Q9WZF4|TM0690 from Thermotoga maritima (149 aa), FASTA scores: opt: 326, E(): 3.4e-13, (40.4% identity in 151 aa overlap); Q9PHU3|CJ0573 from Campylobacter jejuni (147 aa), FASTA scores: opt:290, E(): 5.1e-11, (36.4% identity in 151 aa overlap); etc. Also some similarity to upstream O69654|Rv3686c|MTV025.034c conserved hypothetical [...]
  
    0.598
Rv1870c
Rv1870c, (MTCY359.03), len: 211 aa. Conserved hypothetical protein. Some similarity to SC6F7.17c hypothetical protein from Streptomyces coelicolor (216 aa).
   
  
 0.577
Rv2585c
Possible conserved lipoprotein; Rv2585c, (MT2662, MTCY227.16), len: 557 aa. Possible conserved lipoprotein precursor, possibly attached to the membrane by a lipid anchor and substrate-binding protein involved in transport, equivalent to Q49646|YP85_MYCLE|ML0489|MLCB1259.07|B1177_C2_197 hypothetical lipoprotein precursor from Mycobacterium leprae (555 aa), FASTA scores: opt: 2812, E(): 9.8e-158,(78.95% identity in 546 aa overlap); and C-terminus highly similar to C-terminus of Q49638|DCIAE|B1177_C1_166 DCIAE protein from Mycobacterium leprae (344 aa), FASTA scores: opt: 1177, E(): 7.4e- [...]
   
  
 0.553
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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