node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0538 | Rv1775 | Rv0538 | Rv1775 | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | Conserved hypothetical protein; Rv1775, (MTCY25C11.02), unknown, len: 272 aa. Conserved hypothetical protein, similar to O28806|AF1466 conserved hypothetical protein from Archaeoglobus fulgidus (255 aa), FASTA scores: opt: 364, E(): 1e-17, (29.2% identity in 267 aa overlap). | 0.761 |
Rv0538 | Rv2113 | Rv0538 | Rv2113 | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | Rv2113, (MTCY261.09), len: 397 aa. Probable integral membrane protein. | 0.755 |
Rv0538 | Rv3254 | Rv0538 | Rv3254 | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | Rv3254, (MTCY20B11.29), len: 462 aa. Conserved hypothetical protein, similar to CAC37877|SC1G7.02 putative secreted protein from Streptomyces coelicolor (440 aa),FASTA scores: opt: 606, E(): 6.2e-31, (31.7% identity in 445 aa overlap); O86550|SC1F2.13c hypothetical 50.7 KDA protein from Streptomyces coelicolor (476 aa), FASTA scores: opt: 577, E(): 4.5e-29, (32.5% identity in 400 aa overlap); Q9L0A8|SCC24.09 putative secreted protein from Streptomyces coelicolor (468 aa), FASTA scores: opt: 380,E(): 1.3e-16, (30.7% identity in 391 aa overlap); BAB48792|MLL1411 probable FAD-dependent mo [...] | 0.642 |
Rv0538 | Rv3732 | Rv0538 | Rv3732 | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | Conserved protein; Rv3732, (MTV025.080), len: 352 aa. Conserved protein. The region between aa 175-352 is highly similar to the region between aa 72-257 of Q9KH39 hypothetical 55.5 KDA protein from Mycobacterium smegmatis (511 aa), FASTA scores: opt: 1122, E(): 7.3e-63, (98.85% identity in 176 aa overlap). Also shows some similarity with Q55304 hypotheticalk protein from Synechocystis sp. strain PCC 6803 (387 aa), FASTA scores: opt: 201, E(): 2.7e-05, (27.1% identity in 251 aa overlap); and P74254|SLR1173 hypothetical 52.5 KDA protein from Synechocystis sp. strain PCC 6803 (463 aa), FA [...] | 0.715 |
Rv0538 | csm4 | Rv0538 | Rv2820c | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRN [...] | 0.404 |
Rv0538 | embR | Rv0538 | Rv1267c | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | Probable transcriptional regulatory protein EmbR; Positively regulates the transcription of the embCAB operon. Exhibits ATPase and GTPase activities; Belongs to the AfsR/DnrI/RedD regulatory family. | 0.662 |
Rv1682 | Rv1754c | Rv1682 | Rv1754c | Rv1682, (MTCI125.04), len: 305 aa. Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. | Conserved protein; Rv1754c, (MTCY28.17c), len: 563 aa. Conserved protein, has proline-rich central region. Some similarity in central region to other Mycobacterium tuberculosis proline-rich proteins e.g. O06555|Rv1157c|MTCI65.24c (371 aa), (32.5% identity in 191 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | 0.669 |
Rv1682 | Rv3096 | Rv1682 | Rv3096 | Rv1682, (MTCI125.04), len: 305 aa. Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | 0.808 |
Rv1682 | Rv3732 | Rv1682 | Rv3732 | Rv1682, (MTCI125.04), len: 305 aa. Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. | Conserved protein; Rv3732, (MTV025.080), len: 352 aa. Conserved protein. The region between aa 175-352 is highly similar to the region between aa 72-257 of Q9KH39 hypothetical 55.5 KDA protein from Mycobacterium smegmatis (511 aa), FASTA scores: opt: 1122, E(): 7.3e-63, (98.85% identity in 176 aa overlap). Also shows some similarity with Q55304 hypotheticalk protein from Synechocystis sp. strain PCC 6803 (387 aa), FASTA scores: opt: 201, E(): 2.7e-05, (27.1% identity in 251 aa overlap); and P74254|SLR1173 hypothetical 52.5 KDA protein from Synechocystis sp. strain PCC 6803 (463 aa), FA [...] | 0.870 |
Rv1682 | csm4 | Rv1682 | Rv2820c | Rv1682, (MTCI125.04), len: 305 aa. Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. | Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRN [...] | 0.760 |
Rv1682 | mmpS1 | Rv1682 | Rv0403c | Rv1682, (MTCI125.04), len: 305 aa. Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. | Rv0403c, (MTCY04D9.16c), len: 142 aa. Probable mmpS1, conserved membrane protein (see citation below),highly similar to other Mycobacterial proteins e.g. YV33_MYCLE|P54880 hypothetical 16.9 kDa protein from Mycobacterium leprae (154 aa), FASTA scores: opt: 458, E(): 1.6e-26, (46.9% identity in 143 aa overlap); YV33_MYCTU|Q11170 hypothetical 15.9 kDa protein from Mycobacterium tuberculosis (147 aa), FASTA scores: opt: 362, E(): 1.1e-19, (42.1% identity in 140 aa overlap); etc. Also similar to other MmpS proteins from Mycobacterium tuberculosis e.g. Rv0677c, Rv0451c, etc. Belongs to the [...] | 0.656 |
Rv1754c | Rv1682 | Rv1754c | Rv1682 | Conserved protein; Rv1754c, (MTCY28.17c), len: 563 aa. Conserved protein, has proline-rich central region. Some similarity in central region to other Mycobacterium tuberculosis proline-rich proteins e.g. O06555|Rv1157c|MTCI65.24c (371 aa), (32.5% identity in 191 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Rv1682, (MTCI125.04), len: 305 aa. Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. | 0.669 |
Rv1754c | Rv3096 | Rv1754c | Rv3096 | Conserved protein; Rv1754c, (MTCY28.17c), len: 563 aa. Conserved protein, has proline-rich central region. Some similarity in central region to other Mycobacterium tuberculosis proline-rich proteins e.g. O06555|Rv1157c|MTCI65.24c (371 aa), (32.5% identity in 191 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | 0.556 |
Rv1754c | Rv3732 | Rv1754c | Rv3732 | Conserved protein; Rv1754c, (MTCY28.17c), len: 563 aa. Conserved protein, has proline-rich central region. Some similarity in central region to other Mycobacterium tuberculosis proline-rich proteins e.g. O06555|Rv1157c|MTCI65.24c (371 aa), (32.5% identity in 191 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Conserved protein; Rv3732, (MTV025.080), len: 352 aa. Conserved protein. The region between aa 175-352 is highly similar to the region between aa 72-257 of Q9KH39 hypothetical 55.5 KDA protein from Mycobacterium smegmatis (511 aa), FASTA scores: opt: 1122, E(): 7.3e-63, (98.85% identity in 176 aa overlap). Also shows some similarity with Q55304 hypotheticalk protein from Synechocystis sp. strain PCC 6803 (387 aa), FASTA scores: opt: 201, E(): 2.7e-05, (27.1% identity in 251 aa overlap); and P74254|SLR1173 hypothetical 52.5 KDA protein from Synechocystis sp. strain PCC 6803 (463 aa), FA [...] | 0.696 |
Rv1754c | csm4 | Rv1754c | Rv2820c | Conserved protein; Rv1754c, (MTCY28.17c), len: 563 aa. Conserved protein, has proline-rich central region. Some similarity in central region to other Mycobacterium tuberculosis proline-rich proteins e.g. O06555|Rv1157c|MTCI65.24c (371 aa), (32.5% identity in 191 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRN [...] | 0.550 |
Rv1754c | mmpS1 | Rv1754c | Rv0403c | Conserved protein; Rv1754c, (MTCY28.17c), len: 563 aa. Conserved protein, has proline-rich central region. Some similarity in central region to other Mycobacterium tuberculosis proline-rich proteins e.g. O06555|Rv1157c|MTCI65.24c (371 aa), (32.5% identity in 191 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Rv0403c, (MTCY04D9.16c), len: 142 aa. Probable mmpS1, conserved membrane protein (see citation below),highly similar to other Mycobacterial proteins e.g. YV33_MYCLE|P54880 hypothetical 16.9 kDa protein from Mycobacterium leprae (154 aa), FASTA scores: opt: 458, E(): 1.6e-26, (46.9% identity in 143 aa overlap); YV33_MYCTU|Q11170 hypothetical 15.9 kDa protein from Mycobacterium tuberculosis (147 aa), FASTA scores: opt: 362, E(): 1.1e-19, (42.1% identity in 140 aa overlap); etc. Also similar to other MmpS proteins from Mycobacterium tuberculosis e.g. Rv0677c, Rv0451c, etc. Belongs to the [...] | 0.871 |
Rv1775 | Rv0538 | Rv1775 | Rv0538 | Conserved hypothetical protein; Rv1775, (MTCY25C11.02), unknown, len: 272 aa. Conserved hypothetical protein, similar to O28806|AF1466 conserved hypothetical protein from Archaeoglobus fulgidus (255 aa), FASTA scores: opt: 364, E(): 1e-17, (29.2% identity in 267 aa overlap). | Rv0538, (MTCY25D10.17), len: 548 aa. Possible conserved membrane protein. Middle region highly similar to AAB63811.1|AF009829|MBE4863a|O32850 unknown protein from Mycobacterium bovis (295 aa) possible transmembrane protein with a repetitive proline, threonine-rich region at C-terminus. | 0.761 |
Rv1775 | Rv2113 | Rv1775 | Rv2113 | Conserved hypothetical protein; Rv1775, (MTCY25C11.02), unknown, len: 272 aa. Conserved hypothetical protein, similar to O28806|AF1466 conserved hypothetical protein from Archaeoglobus fulgidus (255 aa), FASTA scores: opt: 364, E(): 1e-17, (29.2% identity in 267 aa overlap). | Rv2113, (MTCY261.09), len: 397 aa. Probable integral membrane protein. | 0.740 |
Rv1775 | Rv3254 | Rv1775 | Rv3254 | Conserved hypothetical protein; Rv1775, (MTCY25C11.02), unknown, len: 272 aa. Conserved hypothetical protein, similar to O28806|AF1466 conserved hypothetical protein from Archaeoglobus fulgidus (255 aa), FASTA scores: opt: 364, E(): 1e-17, (29.2% identity in 267 aa overlap). | Rv3254, (MTCY20B11.29), len: 462 aa. Conserved hypothetical protein, similar to CAC37877|SC1G7.02 putative secreted protein from Streptomyces coelicolor (440 aa),FASTA scores: opt: 606, E(): 6.2e-31, (31.7% identity in 445 aa overlap); O86550|SC1F2.13c hypothetical 50.7 KDA protein from Streptomyces coelicolor (476 aa), FASTA scores: opt: 577, E(): 4.5e-29, (32.5% identity in 400 aa overlap); Q9L0A8|SCC24.09 putative secreted protein from Streptomyces coelicolor (468 aa), FASTA scores: opt: 380,E(): 1.3e-16, (30.7% identity in 391 aa overlap); BAB48792|MLL1411 probable FAD-dependent mo [...] | 0.436 |
Rv1775 | Rv3732 | Rv1775 | Rv3732 | Conserved hypothetical protein; Rv1775, (MTCY25C11.02), unknown, len: 272 aa. Conserved hypothetical protein, similar to O28806|AF1466 conserved hypothetical protein from Archaeoglobus fulgidus (255 aa), FASTA scores: opt: 364, E(): 1e-17, (29.2% identity in 267 aa overlap). | Conserved protein; Rv3732, (MTV025.080), len: 352 aa. Conserved protein. The region between aa 175-352 is highly similar to the region between aa 72-257 of Q9KH39 hypothetical 55.5 KDA protein from Mycobacterium smegmatis (511 aa), FASTA scores: opt: 1122, E(): 7.3e-63, (98.85% identity in 176 aa overlap). Also shows some similarity with Q55304 hypotheticalk protein from Synechocystis sp. strain PCC 6803 (387 aa), FASTA scores: opt: 201, E(): 2.7e-05, (27.1% identity in 251 aa overlap); and P74254|SLR1173 hypothetical 52.5 KDA protein from Synechocystis sp. strain PCC 6803 (463 aa), FA [...] | 0.591 |