node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1060 | Rv3768 | Rv1060 | Rv3768 | Unknown protein; Rv1060, (MTV017.13), len: 157 aa. Unknown protein. | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | 0.560 |
Rv1060 | Rv3899c | Rv1060 | Rv3899c | Unknown protein; Rv1060, (MTV017.13), len: 157 aa. Unknown protein. | Rv3899c, (MTCY15F10.13), len: 410 aa. Conserved hypothetical protein, similar in part to proteins from Mycobacterium tuberculosis strains H37Rv and CDC1551. Region between aa 29-80 is strictly identical to P96909 hypothetical 15.1 KDA protein (fragment) (143 aa) FASTA scores: opt: 562, E(): 4e-16, (69.0% identity in 142 aa overlap); and the N-terminal end is highly similar, but longer 65 aa, to O07266 hypothetical 13.7 KDA protein (fragment) (143 aa), FASTA scores: opt: 562, E(): 4e-16,(69.0% identity in 142 aa overlap). Highly similar to C-terminal end of Q10690|YK82_MYCTU|Rv2082|MTCY [...] | 0.686 |
Rv1060 | eccD2 | Rv1060 | Rv3887c | Unknown protein; Rv1060, (MTV017.13), len: 157 aa. Unknown protein. | ESX-2 secretion system protein eccD2; Rv3887c, (MTCY15F10.25), len: 509 aa. eccD2, esx conserved component, ESX-2 type VII secretion system protein, probable transmembrane protein (has hydrophilic stretch from ~1-130 then very hydrophobic domain), similar to other membrane proteins and with weak similarity to known transporters, e.g. Q9CBV2|ML1539 probable membrane protein from Mycobacterium leprae (503 aa), FASTA scores: opt: 395, E(): 2.3e-16, (28.0% identity in 496 aa overlap); Q9CD35|ML2529 conserved membrane protein from Mycobacterium leprae (485 aa), FASTA scores: opt: 221, E(): [...] | 0.470 |
Rv2561 | Rv3768 | Rv2561 | Rv3768 | Rv2561, (MTCY9C4.07c), len: 97 aa. Conserved hypothetical protein, highly similar in part (and longer 33 aa) to upstream ORF AAK46951|RV2562|MT2638|MTCY9C4.06c conserved hypothetical protein from Mycobacterium tuberculosis (212 aa), FASTA scores: opt: 205, E(): 2e-06,(76.1% identity in 46 aa overlap). | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | 0.552 |
Rv2561 | Rv3899c | Rv2561 | Rv3899c | Rv2561, (MTCY9C4.07c), len: 97 aa. Conserved hypothetical protein, highly similar in part (and longer 33 aa) to upstream ORF AAK46951|RV2562|MT2638|MTCY9C4.06c conserved hypothetical protein from Mycobacterium tuberculosis (212 aa), FASTA scores: opt: 205, E(): 2e-06,(76.1% identity in 46 aa overlap). | Rv3899c, (MTCY15F10.13), len: 410 aa. Conserved hypothetical protein, similar in part to proteins from Mycobacterium tuberculosis strains H37Rv and CDC1551. Region between aa 29-80 is strictly identical to P96909 hypothetical 15.1 KDA protein (fragment) (143 aa) FASTA scores: opt: 562, E(): 4e-16, (69.0% identity in 142 aa overlap); and the N-terminal end is highly similar, but longer 65 aa, to O07266 hypothetical 13.7 KDA protein (fragment) (143 aa), FASTA scores: opt: 562, E(): 4e-16,(69.0% identity in 142 aa overlap). Highly similar to C-terminal end of Q10690|YK82_MYCTU|Rv2082|MTCY [...] | 0.694 |
Rv2561 | eccD2 | Rv2561 | Rv3887c | Rv2561, (MTCY9C4.07c), len: 97 aa. Conserved hypothetical protein, highly similar in part (and longer 33 aa) to upstream ORF AAK46951|RV2562|MT2638|MTCY9C4.06c conserved hypothetical protein from Mycobacterium tuberculosis (212 aa), FASTA scores: opt: 205, E(): 2e-06,(76.1% identity in 46 aa overlap). | ESX-2 secretion system protein eccD2; Rv3887c, (MTCY15F10.25), len: 509 aa. eccD2, esx conserved component, ESX-2 type VII secretion system protein, probable transmembrane protein (has hydrophilic stretch from ~1-130 then very hydrophobic domain), similar to other membrane proteins and with weak similarity to known transporters, e.g. Q9CBV2|ML1539 probable membrane protein from Mycobacterium leprae (503 aa), FASTA scores: opt: 395, E(): 2.3e-16, (28.0% identity in 496 aa overlap); Q9CD35|ML2529 conserved membrane protein from Mycobacterium leprae (485 aa), FASTA scores: opt: 221, E(): [...] | 0.596 |
Rv3169 | Rv3768 | Rv3169 | Rv3768 | Conserved protein; Rv3169, (MTV014.13), len: 374 aa. Conserved protein,with similarity to other hypothetical proteins: Q9A8W6|CC1232 from Caulobacter crescentus (368 aa), FASTA scores: opt: 669, E(): 3.3e-34, (34.05% identity in 376 aa overlap); and O32901|MLCB1779.41 from Mycobacterium leprae (127 aa), FASTA scores: opt: 179, E(): 0.00034, (29.0% identity in 131 aa overlap). Also weak similarity with P95149|Rv1866|MTCY359.07c (804 aa), FASTA scores: opt: 121,E(): 6.4, (37.0% identity in 119 aa overlap). Equivalent to AAK47597 from Mycobacterium tuberculosis strain CDC1551 but shorter 43 aa. | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | 0.906 |
Rv3767c | Rv3768 | Rv3767c | Rv3768 | Possible S-adenosylmethionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | 0.549 |
Rv3768 | Rv1060 | Rv3768 | Rv1060 | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Unknown protein; Rv1060, (MTV017.13), len: 157 aa. Unknown protein. | 0.560 |
Rv3768 | Rv2561 | Rv3768 | Rv2561 | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Rv2561, (MTCY9C4.07c), len: 97 aa. Conserved hypothetical protein, highly similar in part (and longer 33 aa) to upstream ORF AAK46951|RV2562|MT2638|MTCY9C4.06c conserved hypothetical protein from Mycobacterium tuberculosis (212 aa), FASTA scores: opt: 205, E(): 2e-06,(76.1% identity in 46 aa overlap). | 0.552 |
Rv3768 | Rv3169 | Rv3768 | Rv3169 | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Conserved protein; Rv3169, (MTV014.13), len: 374 aa. Conserved protein,with similarity to other hypothetical proteins: Q9A8W6|CC1232 from Caulobacter crescentus (368 aa), FASTA scores: opt: 669, E(): 3.3e-34, (34.05% identity in 376 aa overlap); and O32901|MLCB1779.41 from Mycobacterium leprae (127 aa), FASTA scores: opt: 179, E(): 0.00034, (29.0% identity in 131 aa overlap). Also weak similarity with P95149|Rv1866|MTCY359.07c (804 aa), FASTA scores: opt: 121,E(): 6.4, (37.0% identity in 119 aa overlap). Equivalent to AAK47597 from Mycobacterium tuberculosis strain CDC1551 but shorter 43 aa. | 0.906 |
Rv3768 | Rv3767c | Rv3768 | Rv3767c | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Possible S-adenosylmethionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.549 |
Rv3768 | Rv3899c | Rv3768 | Rv3899c | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Rv3899c, (MTCY15F10.13), len: 410 aa. Conserved hypothetical protein, similar in part to proteins from Mycobacterium tuberculosis strains H37Rv and CDC1551. Region between aa 29-80 is strictly identical to P96909 hypothetical 15.1 KDA protein (fragment) (143 aa) FASTA scores: opt: 562, E(): 4e-16, (69.0% identity in 142 aa overlap); and the N-terminal end is highly similar, but longer 65 aa, to O07266 hypothetical 13.7 KDA protein (fragment) (143 aa), FASTA scores: opt: 562, E(): 4e-16,(69.0% identity in 142 aa overlap). Highly similar to C-terminal end of Q10690|YK82_MYCTU|Rv2082|MTCY [...] | 0.677 |
Rv3768 | accD3 | Rv3768 | Rv0904c | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.684 |
Rv3768 | dprE1 | Rv3768 | Rv3790 | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Decaprenylphosphoryl-beta-D-ribose 2'-oxidase; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D- arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through [...] | 0.586 |
Rv3768 | eccD2 | Rv3768 | Rv3887c | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | ESX-2 secretion system protein eccD2; Rv3887c, (MTCY15F10.25), len: 509 aa. eccD2, esx conserved component, ESX-2 type VII secretion system protein, probable transmembrane protein (has hydrophilic stretch from ~1-130 then very hydrophobic domain), similar to other membrane proteins and with weak similarity to known transporters, e.g. Q9CBV2|ML1539 probable membrane protein from Mycobacterium leprae (503 aa), FASTA scores: opt: 395, E(): 2.3e-16, (28.0% identity in 496 aa overlap); Q9CD35|ML2529 conserved membrane protein from Mycobacterium leprae (485 aa), FASTA scores: opt: 221, E(): [...] | 0.549 |
Rv3768 | glcB | Rv3768 | Rv1837c | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Malate synthase G GlcB; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA. | 0.528 |
Rv3768 | qcrB | Rv3768 | Rv2196 | Unknown protein; Rv3768, (MTCY13D12.02), len: 119 aa. Unknown protein. | Probable ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit); Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. The cytochrome b subunit contains two ubiquinol reactive sites: the oxidation (QP) site and the reduction (QN) site. | 0.549 |
Rv3899c | Rv1060 | Rv3899c | Rv1060 | Rv3899c, (MTCY15F10.13), len: 410 aa. Conserved hypothetical protein, similar in part to proteins from Mycobacterium tuberculosis strains H37Rv and CDC1551. Region between aa 29-80 is strictly identical to P96909 hypothetical 15.1 KDA protein (fragment) (143 aa) FASTA scores: opt: 562, E(): 4e-16, (69.0% identity in 142 aa overlap); and the N-terminal end is highly similar, but longer 65 aa, to O07266 hypothetical 13.7 KDA protein (fragment) (143 aa), FASTA scores: opt: 562, E(): 4e-16,(69.0% identity in 142 aa overlap). Highly similar to C-terminal end of Q10690|YK82_MYCTU|Rv2082|MTCY [...] | Unknown protein; Rv1060, (MTV017.13), len: 157 aa. Unknown protein. | 0.686 |
Rv3899c | Rv2561 | Rv3899c | Rv2561 | Rv3899c, (MTCY15F10.13), len: 410 aa. Conserved hypothetical protein, similar in part to proteins from Mycobacterium tuberculosis strains H37Rv and CDC1551. Region between aa 29-80 is strictly identical to P96909 hypothetical 15.1 KDA protein (fragment) (143 aa) FASTA scores: opt: 562, E(): 4e-16, (69.0% identity in 142 aa overlap); and the N-terminal end is highly similar, but longer 65 aa, to O07266 hypothetical 13.7 KDA protein (fragment) (143 aa), FASTA scores: opt: 562, E(): 4e-16,(69.0% identity in 142 aa overlap). Highly similar to C-terminal end of Q10690|YK82_MYCTU|Rv2082|MTCY [...] | Rv2561, (MTCY9C4.07c), len: 97 aa. Conserved hypothetical protein, highly similar in part (and longer 33 aa) to upstream ORF AAK46951|RV2562|MT2638|MTCY9C4.06c conserved hypothetical protein from Mycobacterium tuberculosis (212 aa), FASTA scores: opt: 205, E(): 2e-06,(76.1% identity in 46 aa overlap). | 0.694 |