node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0081 | Rv3787c | Rv0081 | Rv3787c | Rv0081, (MTV030.25), len: 114 aa. Probable transcriptional regulator, highly similar to others. | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.410 |
Rv3786c | Rv3787c | Rv3786c | Rv3787c | Unknown protein; Rv3786c, (MTCY13D12.20), len: 407 aa. Unknown protein. Segment between aa 265-300 (approximately) is highly similar to part of O03937|RORF1608 minor capsid protein from Bacteriophage phig1e (1608 aa), FASTA scores: opt: 242, E(): 8.4e-07, (26.85% identity in 272 aa overlap); Q9ETT9|ORF36 putative peptidase from Corynebacterium equii (Rhodococcus equi) plasmid pREAT701 (p33701) and Plasmid virulence (546 aa), FASTA scores: opt: 231, E(): 1.6e-06, (34.15% identity in 167 aa overlap); O69910|SC2E1.40c hypothetical 22.8 KDA protein. from Streptomyces coelicolor (226 aa) FA [...] | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.865 |
Rv3786c | Rv3788 | Rv3786c | Rv3788 | Unknown protein; Rv3786c, (MTCY13D12.20), len: 407 aa. Unknown protein. Segment between aa 265-300 (approximately) is highly similar to part of O03937|RORF1608 minor capsid protein from Bacteriophage phig1e (1608 aa), FASTA scores: opt: 242, E(): 8.4e-07, (26.85% identity in 272 aa overlap); Q9ETT9|ORF36 putative peptidase from Corynebacterium equii (Rhodococcus equi) plasmid pREAT701 (p33701) and Plasmid virulence (546 aa), FASTA scores: opt: 231, E(): 1.6e-06, (34.15% identity in 167 aa overlap); O69910|SC2E1.40c hypothetical 22.8 KDA protein. from Streptomyces coelicolor (226 aa) FA [...] | Hypothetical protein; Rv3788, (MTCY13D12.22), len: 161 aa. Hypothetical unknown protein. | 0.485 |
Rv3787c | Rv0081 | Rv3787c | Rv0081 | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Rv0081, (MTV030.25), len: 114 aa. Probable transcriptional regulator, highly similar to others. | 0.410 |
Rv3787c | Rv3786c | Rv3787c | Rv3786c | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Unknown protein; Rv3786c, (MTCY13D12.20), len: 407 aa. Unknown protein. Segment between aa 265-300 (approximately) is highly similar to part of O03937|RORF1608 minor capsid protein from Bacteriophage phig1e (1608 aa), FASTA scores: opt: 242, E(): 8.4e-07, (26.85% identity in 272 aa overlap); Q9ETT9|ORF36 putative peptidase from Corynebacterium equii (Rhodococcus equi) plasmid pREAT701 (p33701) and Plasmid virulence (546 aa), FASTA scores: opt: 231, E(): 1.6e-06, (34.15% identity in 167 aa overlap); O69910|SC2E1.40c hypothetical 22.8 KDA protein. from Streptomyces coelicolor (226 aa) FA [...] | 0.865 |
Rv3787c | Rv3788 | Rv3787c | Rv3788 | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Hypothetical protein; Rv3788, (MTCY13D12.22), len: 161 aa. Hypothetical unknown protein. | 0.492 |
Rv3787c | cmaA1 | Rv3787c | Rv3392c | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Cyclopropane mycolic acid synthase 1; Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. | 0.630 |
Rv3787c | cmaA2 | Rv3787c | Rv0503c | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Cyclopropane mycolic acid synthase 2; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envel [...] | 0.433 |
Rv3787c | mmaA1 | Rv3787c | Rv0645c | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Mycolic acid methyltransferase MmaA1; Involved in the conversion of a cis-olefin into a trans- olefin with concomitant introduction of an allylic methyl branch at the proximal position of the precursor to both the methoxy and ketomycolic acids. It directly affects the cis- to trans ratio and indirectly affects the keto to methoxy ratio; Belongs to the CFA/CMAS family. | 0.547 |
Rv3787c | mmaA2 | Rv3787c | Rv0644c | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | Cyclopropane mycolic acid synthase MmaA2; Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. MmaA2 also catalyzes the biosynthesis of the cis-cyclopropanated methoxymycolates. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. | 0.437 |
Rv3788 | Rv3786c | Rv3788 | Rv3786c | Hypothetical protein; Rv3788, (MTCY13D12.22), len: 161 aa. Hypothetical unknown protein. | Unknown protein; Rv3786c, (MTCY13D12.20), len: 407 aa. Unknown protein. Segment between aa 265-300 (approximately) is highly similar to part of O03937|RORF1608 minor capsid protein from Bacteriophage phig1e (1608 aa), FASTA scores: opt: 242, E(): 8.4e-07, (26.85% identity in 272 aa overlap); Q9ETT9|ORF36 putative peptidase from Corynebacterium equii (Rhodococcus equi) plasmid pREAT701 (p33701) and Plasmid virulence (546 aa), FASTA scores: opt: 231, E(): 1.6e-06, (34.15% identity in 167 aa overlap); O69910|SC2E1.40c hypothetical 22.8 KDA protein. from Streptomyces coelicolor (226 aa) FA [...] | 0.485 |
Rv3788 | Rv3787c | Rv3788 | Rv3787c | Hypothetical protein; Rv3788, (MTCY13D12.22), len: 161 aa. Hypothetical unknown protein. | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.492 |
cmaA1 | Rv3787c | Rv3392c | Rv3787c | Cyclopropane mycolic acid synthase 1; Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.630 |
cmaA2 | Rv3787c | Rv0503c | Rv3787c | Cyclopropane mycolic acid synthase 2; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envel [...] | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.433 |
mmaA1 | Rv3787c | Rv0645c | Rv3787c | Mycolic acid methyltransferase MmaA1; Involved in the conversion of a cis-olefin into a trans- olefin with concomitant introduction of an allylic methyl branch at the proximal position of the precursor to both the methoxy and ketomycolic acids. It directly affects the cis- to trans ratio and indirectly affects the keto to methoxy ratio; Belongs to the CFA/CMAS family. | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.547 |
mmaA1 | mmaA2 | Rv0645c | Rv0644c | Mycolic acid methyltransferase MmaA1; Involved in the conversion of a cis-olefin into a trans- olefin with concomitant introduction of an allylic methyl branch at the proximal position of the precursor to both the methoxy and ketomycolic acids. It directly affects the cis- to trans ratio and indirectly affects the keto to methoxy ratio; Belongs to the CFA/CMAS family. | Cyclopropane mycolic acid synthase MmaA2; Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. MmaA2 also catalyzes the biosynthesis of the cis-cyclopropanated methoxymycolates. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. | 0.530 |
mmaA2 | Rv3787c | Rv0644c | Rv3787c | Cyclopropane mycolic acid synthase MmaA2; Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. MmaA2 also catalyzes the biosynthesis of the cis-cyclopropanated methoxymycolates. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. | Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. | 0.437 |
mmaA2 | mmaA1 | Rv0644c | Rv0645c | Cyclopropane mycolic acid synthase MmaA2; Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. MmaA2 also catalyzes the biosynthesis of the cis-cyclopropanated methoxymycolates. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. | Mycolic acid methyltransferase MmaA1; Involved in the conversion of a cis-olefin into a trans- olefin with concomitant introduction of an allylic methyl branch at the proximal position of the precursor to both the methoxy and ketomycolic acids. It directly affects the cis- to trans ratio and indirectly affects the keto to methoxy ratio; Belongs to the CFA/CMAS family. | 0.530 |