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There are several matches for 'Tle1'.
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176 matches
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protein
1)
Homo sapiens
TLE1
- Transducin-like enhancer protein 1; Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. Belongs to the WD repeat Groucho/TLE family.
2)
Mus musculus
Tle1
- Transducin-like enhancer protein 1; Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG (By similarity); Belongs to the WD repeat Groucho/TLE family.
3)
Homo sapiens
LEF1 - Lymphoid enhancer-binding factor 1; Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis.
TLE1
, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domain and may be an antagonist for Wnt signaling. Isoform 5 [...]
[a.k.a. ENST00000509428, R-HSA-162582, R-HSA-195253]
4)
Homo sapiens
TCF7 - Transcription factor 7; Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes.
TLE1
, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
[a.k.a. ENST00000521639, XM_006714685, TCF7-205]
5)
Homo sapiens
TCF7L2 - Transcription factor 7-like 2; Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1.
TLE1
, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of [...]
[a.k.a. EAW49515.1, CAB97213.1, TCF7L2-209]
6)
Acanthochromis polyacanthus
TLE1
- Uncharacterized protein.
7)
Ailuropoda melanoleuca
TLE1
- TLE family member 1, transcriptional corepressor.
8)
Alligator mississippiensis
TLE1
- Transducin-like enhancer protein 1 isoform A.
9)
Alligator sinensis
TLE1
- Transducin-like enhancer protein 1 isoform X1.
10)
Amphiprion ocellaris
TLE1
- Uncharacterized protein.
11)
Amphiprion percula
TLE1
- Uncharacterized protein.
12)
Anas platyrhynchos
TLE1
- TLE family member 1, transcriptional corepressor.
13)
Anser cygnoides
TLE1
- LOW QUALITY PROTEIN: transducin-like enhancer protein 1.
14)
Aotus nancymaae
TLE1
- Uncharacterized protein.
15)
Apteryx rowi
TLE1
- TLE family member 1, transcriptional corepressor.
16)
Aquila chrysaetos
TLE1
- TLE family member 1, transcriptional corepressor.
17)
Betta splendens
TLE1
- Transducin-like enhancer protein 1.
18)
Bison bison
TLE1
- TLE family member 1, transcriptional corepressor.
19)
Bos grunniens
TLE1
- TLE family member 1, transcriptional corepressor.
20)
Bos indicus
TLE1
- TLE family member 1, transcriptional corepressor.
176 matches
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