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366 matches
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protein
1)
Homo sapiens
MSH2 - DNA mismatch repair protein Msh2; Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers
bend
the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a t [...]
[a.k.a. UPI000D1971F5, ENSP00000389452, ENST00000406134]
2)
Homo sapiens
MSH6 - DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha
bends
the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, a [...]
[a.k.a. HPA028446, XP_024308589.1, XP_024308590]
3)
Homo sapiens
MTERF1 - Transcription termination factor 1, mitochondrial; Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA
bending
and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand; Belongs to the mTERF family.
[a.k.a. ENST00000442961, NP_001288063.1, MTERF]
4)
Homo sapiens
MSH3 - DNA mismatch repair protein Msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer
bends
the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, a [...]
[a.k.a. AC010270, DNA mismatch repair protein Msh3, 3THW]
5)
Homo sapiens
SAP30L - Histone deacetylase complex subunit SAP30L; [Isoform 1]: Functions as transcription repressor, probably via its interaction with histone deacetylase complexes. Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus. Binds DNA, apparently without sequence-specificity, and
bends
bound double-stranded DNA. Binds phosphoinositol phosphates (phosphoinositol 3- phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import. [Isoform 3]: Functions as [...]
[a.k.a. SAP30 like, ENST00000297109, NP_078908]
6)
Homo sapiens
SOX17 - Transcription factor SOX-17; Acts as transcription regulator that binds target promoter DNA and
bends
the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'- AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal development of the definitive gut endoderm. Required for normal looping of the embryonic heart tube. Plays an important role in embryonic and postnatal vascular development, including development of arteries. Plays an important rol [...]
[a.k.a. NP_071899, R-HSA-162582, NM_022454.4]
7)
Homo sapiens
RETREG1 - Reticulophagy regulator 1; Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane
bending
capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Required for long-term survival of nociceptive and autonomic ganglion neurons.
[a.k.a. XP_024301886.1, NP_001030022, ENSP00000425089]
8)
Homo sapiens
CNBD2 - Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar
bending
of sperm.
[a.k.a. NP_543024.2, ENST00000349339, ENST00000622112.4]
9)
Homo sapiens
SRY - Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA
bending
. SRY HMG box recognizes DNA by partia [...]
[a.k.a. JQ811905, 2GZK, NM_003140.2]
10)
Homo sapiens
FCHO2 - F-BAR domain only protein 2; Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-
bending
activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2- dependen [...]
[a.k.a. ENST00000430046, XM_017009016, 115548]
11)
Homo sapiens
REPIN1 - Replication initiator 1; Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'- ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA
bending
.
[a.k.a. XP_024302506.1, NP_055189.2, XP_024302505.1]
12)
Homo sapiens
FOXC1 - Forkhead box protein C1; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'- [G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA
bending
. Acts as a transcriptional coactivator. Stimulates Indian hedgehog (Ihh)-induced target gene expression mediated by the transcription factor GLI2, and hence regulates endochondral ossification (By s [...]
[a.k.a. CH471087, ARA, Q9NUE5]
13)
Acinetobacter baylyi
benD
- Unannotated protein; Degradation of 2-hydro-1,2-dihydroxy benzoate (DHB) to catechol; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
14)
Acinetobacter guillouiae
benD
- Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
15)
Acinetobacter pittii
benD
- 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
16)
Acinetobacter schindleri
benD
- 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Protein involved in nucleotide binding and metabolic process; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
17)
Agrobacterium sp. SCN6119
benD
- 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
18)
Alcaligenes faecalis
benD
- 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
19)
Alishewanella agri
benD
- COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
20)
Alishewanella jeotgali
benD
- COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
366 matches
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