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There are several matches for 'braF'.
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422 matches
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organism
protein
1)
Homo sapiens
BRAF
- Serine/threonine-protein kinase B-raf; Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. May play a role in the postsynaptic responses of hippocampal neurons ; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
2)
Mus musculus
Braf
- Serine/threonine-protein kinase B-raf; Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. May play a role in the postsynaptic responses of hippocampal neurons.
3)
Homo sapiens
KSR2 - Kinase suppressor of Ras 2; Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Acts as MAP2K1/MEK1-dependent allosteric activator of
BRAF
; upon binding to MAP2K1/MEK1, dimerizes with
BRAF
and promotes
BRAF
-mediated phosphorylation of MAP2K1/MEK1. Interaction with
BRAF
enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, [...]
[a.k.a. R-HSA-162582, NP_775869, kinase suppressor of ras 2]
4)
Homo sapiens
MAP2K2 - Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates
BRAF
in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-
BRAF
dimerization and
BRAF
activation.
[a.k.a. NM_030662, ENST00000394867, OTTHUMG00000134286]
5)
Homo sapiens
KSR1 - Kinase suppressor of Ras 1; Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity). Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of
BRAF
; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with
BRAF
and promotes
BRAF
-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity). Its kinase activity is unsure (By similarity). Some protein [...]
[a.k.a. uc002gzo.2, NM_014238.2, A0A0A0MQW1]
6)
Homo sapiens
MAP3K11 - Mitogen-activated protein kinase kinase kinase 11; Activates the JUN N-terminal pathway. Required for serum- stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen- stimulated phosphorylation and activation of
BRAF
, but does not phosphorylate
BRAF
directly. Influences microtubule organization during the cell cycle.
[a.k.a. ENST00000532507, E9PID4, R-HSA-162582]
7)
Homo sapiens
RNF149 - E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates
BRAF
, inducing its proteasomal degradation.
[a.k.a. UPI0000366F4A, ENST00000478404, XR_001738713.2]
8)
Homo sapiens
DGKH - Diacylglycerol kinase eta; Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and
BRAF
from cytoplasm to membranes and their heterodimerization.
[a.k.a. R-HSA-388396, NR_123715.2, CCDS55898.1]
9)
Acanthochromis polyacanthus
braf
- B-Raf proto-oncogene, serine/threonine kinase.
10)
Accipiter nisus
BRAF
- B-Raf proto-oncogene, serine/threonine kinase.
11)
Acinetobacter baylyi
braF
- Unannotated protein.
12)
Aeromonas schubertii
braF
- Leucine/isoleucine/valine transporter ATP-binding subunit.
13)
Agrobacterium genomosp.
braF
- High-affinity branched-chain amino acid transport ATP-binding protein
BraF
; Function of homologous gene experimentally demonstrated in an other organism; transporter.
14)
Agrobacterium radiobacter
braF
- Amino acid ABC transporter.
15)
Agrobacterium salinitolerans
braF
- High-affinity branched-chain amino acid transport ATP-binding protein
BraF
; Function of homologous gene experimentally demonstrated in an other organism; transporter.
16)
Agrobacterium sp. NCPPB925
braF
- High-affinity branched-chain amino acid transport ATP-binding protein
BraF
.
17)
Ailuropoda melanoleuca
BRAF
- B-Raf proto-oncogene, serine/threonine kinase.
18)
Alligator mississippiensis
BRAF
- Serine/threonine-protein kinase B-raf.
19)
Alligator sinensis
BRAF
- Serine/threonine-protein kinase B-raf.
20)
Amazona collaria
BRAF
- B-Raf proto-oncogene, serine/threonine kinase.
422 matches
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