STRINGSTRING
Cgl0097 Cgl0097 Cgl0096 Cgl0096 acn acn aceA aceA aceB aceB ilvN ilvN Cgl0050 Cgl0050 Cgl2681 Cgl2681 ilvC ilvC Cgl0021 Cgl0021 ilvD ilvD
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Cgl0097Thiamine pyrophosphate dependent enzyme. (184 aa)    
Predicted Functional Partners:
Cgl0096
Hypothetical protein.
    0.988
acn
ACONITASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2- methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity). ECO:0000250|UniProtKB:Q8ZP52, ; Belongs to the aconitase/IPM isomerase family.
   
 
 0.912
aceA
ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
   
 
 0.905
aceB
MALATE SYNTHASE; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.904
ilvN
ACETOHYDROXYACID SYNTHASE SMALL SUBUNIT.
  
 
 0.852
Cgl0050
FAD MONOOXYGENASE, PHEA/TFDB FAMILY.
  
  
 0.758
Cgl2681
2-polyprenyl-6-methoxyphenol hydroxylase or related FAD-dependent oxidoreductase.
  
  
 0.758
ilvC
KETOL-ACID REDUCTOISOMERASE; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.614
Cgl0021
Protease with chaperone function.
  
     0.572
ilvD
DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family.
  
  
 0.528
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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